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Fibrocystic Disease of the Breast (FDB)

Fibrocystic Disease of the Breast (FDB)

- “Potential link to Breast Cancer”

 

      Fibrocystic Disease of the Breast (FDB) results from an excess number of cells that grow in the breast – it is believed that the increase in cells is due to hormonal stimulation during the menstrual cycle, which can be compounded by toxic build-up in the breast (possibly due to overuse of deodorants or from a tight-fitting bra which prevents proper lymph drainage from the breast

 

 Bras and Breast Cancer

 

      To keep the cell count steady, some cells have to be removed each month - Leftover cells that have not been appropriately destroyed build up over repeated cycles and cause the lumpy, tender breasts, and larger lesions of fibrocystic disease.

 

      ~90% of American women have FDB - of these women, 40% are unaware they have it    (usually detected by biopsy). Most FDB is benign, harmless and has no consequences. However, the longer FDB is present in the breast, the higher the potential risk for development of breast cancer.

 

Over the last 80 years, hundreds of publications have confirmed  statistical

correlations between advanced forms of FDB and subsequent breast cancer

 

      There are grades of FDB - with some of the cells looking more abnormal than in the benign forms. The more abnormal the cells, the greater chance of these cells becoming cancerous over the decades

 

 

Iodine is the trigger mechanism that promotes appropriate cell death

 

      The breasts concentrate iodine when available - several studies have demonstrated a relationship between low iodine intake and fibrocystic disease of the breast (FDB) both in women and laboratory animals. A sufficiency of iodine eliminates the excess cells, enabling the breast to return to its normal resting state as the fibrocystic disease slowly disappears from the breast.

 

Check out this lecture by Dr. David Brownstein about iodine and its deficiency relationship to Breast Cancer: 

 

http://www.youtube.com/watch?v=tZJ9Bcqjgzc

 

If you discover FDB at the age of 45-55, it is likely you have had it for many years, and there is a significant possibility that the cells may convert to cancer cells. The good news is that it can be cleared up completely with a daily intake of iodine.

 Derry, DM, Breast Cancer and iodine Preventing and surviving,Trafford Publishing company, Canada, 2001.

 

      FDB treated with Iodine Supplementation - In 1993 Ghent and Eskin published a landmark paper on the treatment of severe FDB with iodine supplements. This paper was the result of more than 30 years of research by Dr. Bernard. A. Eskin of the Medical College of Pennsylvania in Philadelphia. First in animals and then in humans, he proved FDB is the result of low dietary iodine. He has also shown that FDB can go on to develop into breast cancer.

Ghent WR et al, Iodine replacement in fibrocystic disease of the breast. Can J Surg 1993;

Eskin BA et al, Different tissue responses for iodine and iodide in rat thyroid and mammary glands, Biol Trace Element Res 1995;

Eskin  BA, Iodine metabolism and breast cancer. Trans NY Acad Sci 1970;

Eskin BA, Iodine and breast cancer. Biol Trace Element Res 1983; Eskin BA, Dietary iodine and cancer risk. Lancet 1976; 

Eskin BA et al, Etiology of mammary gland pathophysiology induced by iodine deficiency, Frontiers in thyroidology, 1986.

 

Iodine addresses potential environmental causes of FDB/ Breast cancer

 

      Pesticides, microbes, toxins, etc - if a person has enough iodine flowing through the body systems, the toxins cannot do much damage because iodine does an excellent job of deactivating toxins.

 

      Environmental estrogen look-alikes (xenoestrogens) - it is likely that iodine helps eliminate FDB and ovarian cysts at least partly through it's interaction with estrogens. Iodine helps the body to metabolize ESTRONE (a slightly carcinogenic human estrogen) and 16-alpha-hydroxyestrone (a much more dangerous metabolite of human estrogen) into ESTRIOL, an "anti-carcinogenic" or at worst "neutral" form of human estrogen.

 

 

What is the Iodine Dose for FDB?

 

      FDB Prevention - based on their studies of iodine in women and female rats, Ghent et al and Eskin have estimated that the amount of iodine required for protection against breast cancer and FDB, is at least 20 to 40 times the amount required for control of goiter. Therefore, the MINIMUM amount of iodine required for control and prevention of FDB is equivalent to 0.1 mg/kg body weight/day (this is the amount used by Ghent et al).

 

E.g. the minimum daily amount of iodine for a 110# woman would be 5 mg.

 

      With known FDB – the pertinent question to ask is “What is the optimal amount of iodine that will restore and maintain normal breast function and histology, without any significant side effects and negative impact on thyroid functions?” (In Canada, 1975, Ghent et al tested various amounts of various forms of iodine in three open trials.  5% Lugol’s solution was used in 233 patients for 2 years in daily amounts ranging from 31 to 62 mg iodine, achieving clinical improvement in 70% of the patients.

Guy. E. Abraham M.D et al “Optimum Levels of Iodine for Greatest Mental and Physical Health”,     www.optimox.com/pics/Iodine/IOD-01/IOD_01.htm

 

 

Unfortunately, if you have FDB you don't know what type you have without a biopsy. On the other hand, the FDB disappears by taking iodine in adequate daily amounts, so that you are essentially preventing breast cancer from occurring.                                                                   

 

The best response for those with FDB was observed with ingestion of about 50 mg iodine/iodide (E.g. 8 drops 5% Lugol’s Solution or 4 Iodoral™) / day for several months

 (the same dose suggested for reversal of the cancerous phase).

 

 

Summary of results obtained by Vishnyakova et al (Vestn Akad Med Navk SSSR, 21:19-22, 1966) and Ghent et al (Can. J. Surg. 36:453-460, 1993) for objective and subjective improvements of

fibrocystic disease of the breast in response to various dosages of various forms of Iodine or Iodide

 

Study Design

# pts

Duration

Form of I

Daily Dosage

% of pts. w/clinical improvement

% of pts with side effects

Open Trial

200

3 years

Potassium Iodide

10-20 mg

72%

none

reported

Open Trial

233

2 years

Lugol 5%*

5-10 drops

(31-62 mg I)

70%

7%

Open Trial

588

5 years

Iodine Caseinate

10 mg

40%

9.5%

Open Trial

1365

18 months

Aqueous

Solution of

Iodine

0.08 mg/Kg BW

74%

10.9%

Double Blind

PL = 33

I2 = 23

mean of

191 days

Aqueous

Solution of

Iodine

0.08 mg/Kg BW

Object.

PL = -3%

I2 = 65%

Subject.

33%

65%

N / A


PL = Placebo, Pts = Patients

http://www.optimox.com/pics/Iodine/IOD-01/IOD_01.htm#42

 

 

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Female Health Problems Links

 

FEMALE RELATED LINKS:

Pregnancy / Baby Related 

Menstrual Cup - Alternative to pads and tampons

Polycystic Ovarian Syndrome (PCOS)

Bacterial Vaginosis (BV)

Fibrocystic Disease of the Breast (FDB)

Uterine Fibroids

Treatment options when symptoms present

Hirsutism

Vaginal Yeast Infection

Urinary Tract Infection  (UTI)

Interstitial Cystitis (IC) - Painful Bladder Syndrome

Breast Cancer

Endometriosis

 

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