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Neptune 'Krill Oil' - For Omega-3 related Health

Neptune Krill Oil (NKO™) from the Antarctic  

WARNING: If you are allergic to shellfish, have a blood coagulation disorder, or are taking anticoagulants such as Warfarin (Coumadin), do NOT use Krill Oil.

Omega-3 Supplement

Most of the high quality krill oil comes from one producer -Neptune Technologies and Bioresources Inc. Company from Canada. This company uses a patented, proprietary cold-extraction process, which also protects the oil from light, and air, and so by preventing its oxidation, preserves its valuable nutrients. The extremely high quality krill oil obtained is referred to as Neptune Krill Oil. The difference in products from various suppliers is in how they package and deliver the krill oil.

NKO Contains a synergistic balance of fatty acids, functional phospholipids and potent antioxidants

Research Confirms Antarctic NKO is Better than Fish Oil at Providing Essential Omega-3s and Antioxidant

Good article: http://www.healthyfellow.com/283/krill-oil-research/



Krill Oil

Fish Oil

Omega-3 to Omega-6 ratio

15 to 1

3 to 1

Fatty acid form






Omega-3 fatty acid bioavailability


(phospholipid structure of O3's is rapidly absorbed by cells)


Has more EPA/DHA, but much less bioavailable than krill; O3's attached to triglycerides must first be broken down (hydrolyzed) in your gut to DHA and EPA. ~ 80-85 % is not absorbed (causing burp back in 50% of people) and is eliminated via the intestines.

Finally, to be usable, fatty acids absorbed into blood must be attached to phosphatidyl choline by the liver.

Heavy metals, PCBs, pesticides, other contaminants

Naturally free

Needs to be purified -

typically screened for mercury, but still commonly contains PCBS, Dioxin, PDEs, PCPs, toxic metals (cadmium, lead, chromium, arsenic)



(contains antioxidants thatprotect against oxidation)

Easily oxidized(damaged) by light, heat and air

(clear or large plastic bottles likely rancid / how long sitting on shelf?)

Antioxidant Potency

Exceptional –48 x FO


After taste

Not unpleasant

64% report reflux effect

Krill Oil Properties

Omega-3 is in the form of Bioavailable phospholipids - these liposomes act as delivery vans to deliver Omega-3 fatty acids directly to your body's cells, including your brain cells. Phospholipids greatly facilitate the passage of the fatty acid molecules through your intestinal wall, and allow a much easier entrance into cell mitochondria and the cellular nucleus. This makes NKO 30% more available to your cells than fish oil, and as such you don't need as many omega-3 milligrams;

Naturally Toxin Free - Krill are tiny, crustaceans that live in the frigid open waters of Antarctica, which are the cleanest waters on earth; Unlike prawns or shrimp, krill are not bottom-feeders, they feed on tiny plankton (microscopic plants and animals) which float on the ocean surface.

NKO contains “Super”Antioxidants –contains high-level, cell membrane-protecting antioxidants that fish oil does not; in direct ORAC (Oxygen Radical Absorbance Capacity) comparisons - milligram for milligram - the value of Krill Oil was found to be 48 times that of fish oil and 34 times that of Coenzyme Q10.

NKO contains vitamins A and E, and a high 1.5 mg. of the powerful and prized astaxanthan - an immune-supporting carotenoid, which not only protects the oil itself from going rancid (when > 0.2 mg astaxanthan/g of krill oil), it also guards your cell membranes from free radical damage and protects against cataracts, age-related macular degeneration and sunburn;

NKO also contains a unique marine source flavonoid that bonds with astaxanthin and EPA/ DHA allowing direct metabolism and better bioavailability of the antioxidants in NKO;

NKO Phospholipids rich source of Choline - the most predominant phospholipid in NKO is phosphatidylcholine, a potent source of choline. Numerous studies have demonstrated the importance of choline in brain development, learning and memory, and its particular importance for fetal and infant brain development. Choline is the precursor for the vital neurotransmitter acetylcholine (sends nerve signals to the brain), and for trimethylglycine (recognized liver protector) - A shortage of acetylcholine has been associated with brain-related disorders such as Alzheimer's disease and autism.

No Fishy Aftertaste, Reflux or Other Side Effects - Although fish oil consumption commonly has a fishy aftertaste, or produces some fish-flavored reflux or belching, this has not occurred with NKO. No adverse effects have been noted even at high dosages.

Krill Oil is always taken in Capsules – prevents oxygen from damaging its high-level polyunsaturated fatty acids; also you don't have to taste the oil on the way down!

Stability - Patented and proprietary cold extraction process protects omega-3 content from damage. NKO is more stable and more resistant to rancidity than conventional fish oils because it contains protective antioxidants, astaxanthan in particular. This means it will last longer and won't oxidize in your body due to rancidity. Lasts for 2 years at room temperature (Do not refrigerate), since its own antioxidants acts as natural preservatives.

Unlike Cod Liver Oil, NKO does NOT contain Vitamin D - this important antioxidant is best obtained from sun exposure to bare skin, but if your area has insufficient sunshine in winter, you should supplement vitamin D3 (Vitamin D –“The Sunshine Vitamin”) or take cod liver oil in addition to a slightly reduced dose of krill oil.

Studies of Health Benefits Using Neptune Krill Oil

October 2010 Study showed that krill oil has effects similar to fish oil on serum lipids, oxidative stress and inflammation, but at Lower Dose ofEPA and DHA

"A total of 113 participants ... were randomized into three groups. Thirty-six were given 6 capsules of 3g krill oil a day, with 543 mg of EHA and DHA; 40 were given 3 capsules of 1.8g fish oil a day, with 864 mg of EPA and DHA ... The remaining 37 received no supplementation ... [T]here was a significant increase in plasma EPA, DHA, and DPA in both the krill oil and fish oil groups ... and no significant differences were seen between the fish oil and the krill oil groups. The EPA + DHA dose in the krill was 62.8 % of that in the fish oil."

Lipids October 2010 10.1007/s11745-010-3490-4

Emphasis is made that all the following studies used Neptune Krill Oil.

Cholesterol / Heart Health Dramatically Improved with Krill Oil

Results were reported for the double-blind phase II clinical trial comparing NKO to high EPA/DHA fish oil and a placebo.

All subjects had diagnosed hyperlipidemia, a known risk factor for heart disease, and mild to very high blood pressure, with cholesterol levels of 194 - 348 mg/dL.

NKO 1.0-1.5g/dayFish oil 3g/day

A multi-center, McGill University (Canada), 90-day, randomized study, followed by a 90-day, controlled follow-up of the patients in group B (see below). 120 men and women were randomly assigned to one of four 30-patient groups:

Group A - received krill oil at a body mass index (BMI)-dependent daily dosage of 2-3g daily.

Group B - were given 1-1.5 g krill oil daily + Follow-up of 500mg/day (1 softgel) for 90 days

Group C -was given a daily 3g dose of fish oil containing 540 mg EPA and 360mg DHA

Group D - was given a placebo containing microcrystalline cellulose

The study's findings (published in Alternative Medicine Review in 2004):

(1) Krill oil is effective for the management of hyperlipidemia - by significantly reducing total cholesterol, LDL and triglycerides, and increasing HDL levels.

(2) At lower and equal doses of fish oil, NKO was significantly more effective than fish oil in managing lipidemia.

(3) Group that continued for 90 days with 1 daily softgel for maintenance, cut their heart attack risk in half- After taking a maintenance dose of 1 softgel for a further 90 days, those in Group B saw their levels of artery-clogging LDL cholesterol plunge 44% and their triglycerides drop 20%, while levels of artery-clearing HDLs soared 38%.

BuneaR et al, Evaluation of the effects of Neptune Krill oil on the clinical course of hyperlipidemia

Quality of Life Study evaluated benefits of Krill Oil

This study further evaluated life qualities of the participants in Group A in the above cholesterol/heart study -participants answered a 36-question standardized survey at the end of 30 days, 90 days, and 180 days.(Those with a BMI (body mass index) < 32 took 2 softgels daily; those with a BMI > 32 took 3 softgels daily for 90 days)

This survey measured patients'physical function, fatigue, pain, social function, emotional role, mental capacity, general health and physical appearance.The survey, in use since 1998 and published in over 4,000 different studies, was designed to provide statistically valid results.

Physical Appearance

Subjects in the quality of life study (above) reported improvements in several physical attributes -an improvement in the look and feel of their hair, skin and nails, along with a 58% reduction in wrinkling, redness and other skin problems.

Woman's World Magazine, The New Youth Preserver From Under the Sea, May 2004


A double-blind, randomized clinical trial evaluated the effectiveness of NKO for management of premenstrual syndrome (PMS) and dysmenorrhea (painful menstrual periods) - concluded:

–   NKO significantly reduced dysmenorrhea and the physical /emotional symptoms of PMS - significantly more effective than fish oil.

Fotini S. et al, Evaluation of the Effects of Neptune Krill Oil™on the Management of Premenstrual Syndrome and Dysmenorrhea


Study evaluated the effects of NKO on the biomarkers of chronic inflammation and the quality of life of 90 patients with arthritic disease - including rheumatoid arthritis and osteoarthritis. The results of this randomized, double-blind and placebo-controlled study positively indicated that 300 mg of Pure Krill Oil daily may, within 7-14 days:

(1) Alleviate symptoms caused by rheumatoid arthritis and osteoarthritis, including joint pain, stiffness and functional impairment.

(2) Significantly inhibit inflammation as shown by a decrease in C-Reactive Protein ( CRP – a biomarker for inflammation).

Study published in the February 2007 issue of the Journal of the American College of Nutrition

Skin Cancer

NKO significantly prevented skin cancer induced by chronic exposure to UV radiation –according to results of a preliminary randomized and controlled 2002 animal study evaluated the effects of krill oil on UVB-radiation induced skin cancer in mice.

Autoimmune Disease

Study using mice, suggested that krill oil may delay the onset and progression of autoimmune disease (such as lupus) - study published in the journal Lipids in 1994, reported on research done at the University of Texas Health Center's Department of Medicine.


Study-Proven Dose of NKO

1g (2 softgels) NKO

Works best if taken in the morning –taking it after noon may keep you awake.

Omega-3fatty acids in NKO –1g (2 x 500mg capsules) contains 150mg EPA and 90mg DHA. Note, however, that this Omega-3, being bound to phospholipids, is much more bio-available than in fish oil.

Storage / Shelf-Life of NKO

Krill Oil will last up to 2 years.

Do not store it in the freezer or refrigerator - extended exposure to temperatures higher than 100 degrees or lower than 50 degrees diminish effectiveness of the phospholipid ingredients.

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