Nutrition Menubar
GSE
Systemic Proteolytic Enzyme Therapy - Anti-Cancer, Anti-inflammatory, boosts immune function
Systemic/ proteolytic enzyme therapy
Proteolytic enzmes (proteases) catalyze the splitting
of proteins
The major proteolytic enzymes involved in protease therapy:
• Pancreatin (contains
amylase, lipase and trypsin)
• Trypsin (separate
from pancreatin)
• Chymotrypsin
(produced in the body)
• Bromelain (from
the stems of pineapples)
• Papain (derived
from unripe papayas)
• Nattokinase ( from
Natto cheese)
• Serrapeptase (from
the silk worm, also plant-sourced)
or its improved alternative Protease
S (derived from Aspergillus melleus )
Nattokinase
Provides optimal clotting ability in the blood.
Rivalling pharmaceutical drugs, such as warfarin, but without any of
the side effects. Those already on blood thinners need to consult their doctor before
using nattokinase supplements.
Sumi H et al.
Protease S
(alternative to Serrapeptase)
This anti-inflammatory is a viable alternative to salicylates,
ibuprofen and other NSAIDS
Protease S (formally Seasprose )
is an improved alternative to serrapeptase. A specialized
(serine-proteinase) proteolytic enzyme derived from Aspergillus melleus ,
having the ability to:
• Reduce painful inflammation
• Break up mucus.
An OTC cold remedy in Japan
• Relieve respiratory infections.
E.g, bronchitis, pulmonary tuberculosis, pulmonary emphysema,
bronchiolitis and bronchial asthma
• Possible antibacterial
- Manufactured in Japan
and has consistently high quality
- Causes virtually no
intestinal distress and is not affected by stomach acid. i.e.
it does not require enteric coating. Studies have shown it is more effective than
serrapeptase -85 % vs. 65 %.
Bracale G, Selvetella L. Clinical study of the efficacy
of and tolerance to seaprose S in inflammatory venous disease. Minerva Cardioangiol
1996;44(10):515-524.
http://naturalsolutionsradio.com/blog/geraldmartin/proteolytic-enzymes
In vivo studies show Seaprose may help alleviate
pain, swelling and inflammation
- Seaprose
demonstrated potent anti-inflammatory activity, inhibiting
edema, and potent bradykinin (a chemical mediator of inflammation)
decomposition activity - demonstrated an ability
to reduce painful inflammation and break up mucus.
Braga PC, Rampoldi C et al "In vitro rheological
assessment of mucolytic activity induced by seaprose" Pharmacol Res 1990;22(5):611-617
- Patients who took
Seaprose showed significant improvements in bronchial inflammation and in the viscosity
of the mucus (the liquid's rate of resistance to flow).
Of 20 patients assessed with chronic bronchitis, half took Seaprose, half took a
placebo; the researchers assessed the effects by analysing each patient's bronchial
mucus.
Braga PC, Moretti M et al "Effects of seaprose on the
rheology of bronchial mucus in patients with chronic bronchitis" Int J Clin Pharmacol
Res 1993;13(3):179-185
- Seaprose demonstrated
anti-inflammatory activity against many different inflammatory conditions.
Including arthritis, edema, pleurisy (inflammation of the lung
lining), and peritonitis (inflammation of the lining of the abdomen).
Fossati A "Antiinflammatory effects of seaprose-S
on various inflammation models" Drug Exp Clin Res 1999;25(6):263-270
- Seaprose significantly
reduce the pain, edema, cramping, and skin redness associated with inflammation
of the vein (thrombophlebitis, associated with blood clot formation)
Bracale G, Selvetella L "Clinical study of the efficacy
of and tolerance to seaprose S in inflammatory venous disease" Minerva
Cardioangiol 1996;44(10):515-524
Serrapeptase or its alternative Protease S
Serrapeptase or its alternative Protease S may be TOO
STRONG an enzyme for treating cancer cells. Weaker enzymes
don't actually kill cancer cells, they just help the I.S. macrophages identify,
engulf, and destroy cancer cells. Stronger enzymes such as serratiopeptidase would
break up so many cancer cells that the field-clearing benefits of weaker enzymes
would be canceled out.
After a cancer patient is in remission, then serratiopeptidase can help
remove scar tissue or can be used against unrelated inflammation or pain;
Silkworms secrete serrapeptase to dissolve
the silk they produce.
Proven to very effectively break down fibrin
and reduce swelling /inflammation in a number of tissues.
Mazzone A, Catalani M, Costanzo M, Drusian
A, Mandoli A, Russo S, Guarini E, Vesperini G. Evaluation of Serratia
peptidase in acute or chronic inflammation of otorhinolaryngology pathology:
a multicentre, double-blind, randomized trial versus placebo. J Int
Med Res. 1990; 18(5):379-88.
Profoundly reduces pain.
Due to its ability to block the release of pain-inducing
amines from inflamed tissues.
Mazzone A, et al. Evaluation of Serratia peptidase
in acute or chronic inflammation of otorhinolaryngology pathology: a
multicentre, double-blind, randomized trial versus placebo. J Int Med
Res. 1990; 18(5):379-88.
Used in combination with other enzymes plant-sourced
serrapeptase is very successful in treating
One serrapeptase product
sold by Takeda since 1968 as an enzyme anti-inflammatory
for a large number ofuses was voluntarily ,
withdrawn from the Japanese market in 2011
- after double-blind trials concluded that it had no therapeutic
effects on chronic bronchitis or sprained ankles. Unfortunately,
serrapeptase has had reliability problems with the
technology used for enteric-coating of capsules or powders and
also causes intestinal distress.
• Fibromyalgia
• Dissolving arterial plaque
• Postoperative scars/keloids
• Old scars and adhesions
How to supplement systemic/proteolytic enzymes
Use enteric-coated enzymes.
Found to survive journey through stomach
PROTEOLYTIC enzyme activity level
(HUT - hemoglobin units, tyrosine basis)
not weight (mg)
is what counts.
Beware of products listing milligrams
of the enzymes. Ideally, you're looking for 200,000 -300,000 HUT
Good SYSTEMIC enzymes:
• Naturopathic physician Dr. Michael
Murray, author of "How
to Prevent and Treat Cancer With Natural Medicine ", concludes
that systemic enzyme therapy (e.g. against cancer, fibrosis)
should have serrapeptase as a base. Since
it exerts more powerful effects than chymotrypsin and trypsin .
• Other experts in the field lean
towards serrapeptase, but blended with other proteases.
An improved alternative for serrapeptase has recently enter the
market, called Protease S (formerly Seaprose).
Enzymes need Coenzymes to activate them.
Ensure sufficiency of:
•
Magnesium (at least 600mg).
Participates in over 300 enzyme reactions.
•
Zinc (30 mg)
SYSTEMIC (mostly protease)
ENZYMES MUST BE TAKEN ON AN EMPTY STOMACH.
To prevent them being used for digestion; take at least 1 hour
before or 1 ½- 2 hours after a meal.
Effective Doses:
• 15-80 tablets depending on problemtaken
in 3-5 divided doses. Since enzymes are relatively
large molecules, it takes a lot of tablets to fit them in
▪
Cancer requires 70-80/day.
YES, AN EFFECTIVE ORAL ENZYME CANCER THERAPY
REQUIRES A LOT OF ENZYMES!
This site author thinks that this is a factor
which would deter many people from utilizing this therapy
For the
purpose of killing cancer cells, it is emphasized that proteolytic enzyme
supplements must be taken on an EMPTY stomach to allow them to make
it to the bloodstream
and not to be used up digesting proteins .
▪ Acute problem (E.g. injury,
preferable to aspirin). 30 to 50 tablets /day;tapering down
to 15 to 20 tablets /day
▪ Disease prevention / Immune system
boost. 5 tablets/day
Well tolerated without side-effects
• Except
rarely those with protein allergies. Such may
not be able to tolerate enzyme therapy
Discontinue enzyme therapy 24 hours before
anticipated surgery involving blood loss
References www.mercola.com
www.wholebodymed.com