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How to Supplement Iodine for health benefits - Lugols Dosage Guidelines

Iodine “The Universal Medicine”

Guidelines for IODORAL®or Lugol's Dosage


Attaining whole-body iodine sufficiency

Suggested approach to dosage

Support for approx. 12mg supplemental dosage

There is no one-size-fits-all approach to iodine supplementation,

since everyone's needs are different.


Iodine increases thyroid function if you are iodine deficient

Iodine decreases thyroid function if you are iodine sufficient


Iodoral®- is a precisely quantified tablet form of Lugol's solution - containing 5 mg iodine and 7.5 mg iodide as the potassium salt. It is basically the tablet equivalent of 2 drops of Lugol's solution. To prevent gastric irritation, the iodine/iodide preparation was absorbed into a colloidal silica excipient, and to eliminate the taste of iodine, the tablets were coated with a thin film of pharmaceutical glaze.

Attaining whole-body iodine sufficiency

(estimated 1.5g of iodine in the body)

Whole-body iodine sufficiency takes about a year to achieve with a daily intake of 12.5 mg iodine/iodide -i.e. 1 tablet Iodoral®or2 drops Lugol's solution.

It takes about 3 months at 50mg iodine/iodide per day (4 tablets Iodoral®, 8 drops Lugols, best split into 2 morning and afternoon doses) -This is the amount shown to have positive impact on serious illnesses such as breast cancer, thyroid cancer or autoimmune thyroid disorders.

Once whole body sufficiency is attained, 1 tablet Iodoral®or 2 drops Lugols /day will maintain it - in 8 normal subjects who achieved whole body iodine sufficiency, the fasting serum inorganic iodide levels ranged from 0.85 to 1.34 mg/L 24 hrs after the last intake of iodine.

Suggested Approach to dosages

(But use your own judgement)

With a known health problem – start with 12.5 mg iodine/iodide (1 tablet Iodoral®or 2 drops Lugols) and build up slowly, maintaining dose for a few days, to a maximum 50mg iodine/iodide per day (spaced out) according to your body's comfort level, any symptoms indicating excessive intake (see table below), and especially your own intuition. After reaching whole body sufficiency, then cut back slowly on the daily dose until you are at maintenance level.

For guidelines on Lugol's dosage for specific problems:

Lugol's Dosage chart

For maintenance – ~3-12 mg iodine/iodide (¼-1 Iodoral tablet or ½- 2 drops Lugol's) / day should be sufficient for the body's glands and organs.A suggestion is to start with (½Iodoral tablet or 1 drop Lugol's), and make adjustments if necessary.

Adjust the dose downward - if you have any of the following symptoms:

Excess Iodine Symptoms

Excess Thyroid Hormone Symptoms


Acne, rashes*
Increased salivation / runny nose*
Metallic taste in mouth*

Racing pulse


Sweating palms

Oily skin

* An unpleasant brassy taste, runny nose, and acne-like skin lesions are caused by the bromide that iodine extracts from the tissues.

Women tend to need more iodine/iodide than men - The best final dosage of iodide/iodine for most men is 8-12 mg. The best final dosage of iodide/iodine for most women is higher at ~12 mg per day, because the female breast concentrates elemental iodine from available iodide (up to 6mg/day). If this iodine is not discharged into breast milk with breast feeding, it diffuses out of the breast tissues, and is lost at high rates into the urine. Thus, women need ~ 5 mg more dietary iodide per day than men, just to maintain optimal iodide levels.

About 90-95% of American adults can start at the optimum final ~8-12 mg dose with no health problems, but for those with severe hypothyroidism and/or diabetic neuropathy, an initial dose of even 1 mg may be too much – as the iodine restores metabolic function to nerves, the dying peripheral nerves start being revived, which can send increasing amounts of abnormal signals to the brain, often experienced as intense itching and/or phantom pains. As they recover, the nerves eventually start acting more normally, and the pains and itching gradually go away. Unfortunately, the more damage, the longer and more painful is the recovery. To make the recovery bearable, the iodine dose must be low to allow a gradual rebuilding of the nerves over months, or even years.

The requirement for iodine depends on the goitrogenic load - a goitrogen interferes with the uptake and utilization of iodide by target cells. The greater the goitrogenic load, the greater the need for iodine. Examples of goitrogens are bromine, chlorine, fluorine, and soy –all commonly found in today's diet and environment.

Restoring iodine concentrations too quickly may overload body with toxins - Since iodine mobilizes toxic metals and goitrogenic halides from their storage sites, it may not be wise to achieve whole body sufficiency for iodine too rapidly since mobilization of these toxic substances may increase their peripheral levels high enough to cause symptoms.A complete nutritional program combined with increased fluid intake will help the body eliminate these toxic elements more safely.

For those experiencingdetox side effects – such as constipation, acne or rash, often as a result of iodine detoxing bromide into the bloodstream causing bromism symptoms (other bromism symptomsinclude lethargy, depression, "dark" thoughts, brain fog, leg and hip pain):

–    Side-effects are usually reversible in 24-48 hours -by discontinuing the iodine and allowing a short period of washout before restarting at a lower dose;

–    Use 1/2 tsp. Celtic or Himalayan seasalt dissolved in a large glass of water – this speeds upthe bromide detox through the kidneys;

Drink additional water

Support for approx. 12mg supplemental dosage

Dr. Guy Abraham's Optimum Iodine Intake – the optimal daily requirement for iodine has been estimated at:

–   6 mg IODIDE /day for the thyroid gland – the first in line for any available iodine;

–   ~5 mg IODINE /dayfor the mammary glands (breasts)–    more for women heavier than 110#, or with large breasts, less for men;

–   The rest of the body needs ~2 mg /day - such as adrenals, thymus, ovaries hypothalamus, pituitary, others.

The average Japanese diet contains more than 12 mg iodine / day (about 100 x U.S. RDA of 150mcg, and 50 times average U.S. consumption) - Japanese women experience one of the lowest prevalences for breast, ovarian and uterine cancer;

Long-time recommended daily intake for iodine/iodide supplementation was 2 to 6 drops of Lugol solution containing 12.5 to 37.5 mg total iodide - A dose of 0.1 ml (~2 drops) of Lugol's solution contains 5 mg iodine and 7.5 mg iodide as the potassium salt, the near perfect total amount of iodine and ratio of iodine to iodide, for sufficiency of the thyroid and mammary glands;

The high iodine intake of the Japanese would be needed to handle the toxins from their heavy seafood consumption (Many of the types eaten being from the water “clean-up crew”, without fins and scales e.g. shellfish) - on the other hand, the Western population need the iodine to deal with the now high (but previously uncommon) exposure to halogens (bromine, chlorine, fluorine) and soy in their diet and environment.

Safety record is 6 grams IN-organic (i.e. not organic) iodine /day - Daily amounts of up to 6 g /day of INorganic iodine have been safely taken by large groups of patients for several years. It is important however to emphasize that this safety record only applies to INorganic, non-radioactive iodine/iodide, not to organic iodine-containing drugs and to radioactive iodides (radioiodides). Obtaining high doses of organic iodine from seaweed and organic iodine supplements, have sometimes resulted in toxicity problems. Dr. Abraham contributes this, not to the iodine, but to excess doses of the molecule to which the iodine is attached.

Some good references for dosage research

IODINE related links


Related Links

IODINE –The Universal Medicine

About Iodine

-Health Functions

"Iodine at work in the body”

- Other Uses for Iodine


About Iodine deficiency

“Common and affects more than thyroid”

–    Why are we Iodine Deficient?

- Goitrogens vs. Iodine

–    Symptoms of Iodine Deficiency

–    Iodine Sufficiency tests


About Iodine Health Benefits

- Chart of Health Benefits

-Iodine against thyroid disorders

-Iodine against cancer


About How to Supplement Iodine

-Sources of Iodine/Iodide

-Lugols Dosage Guidelines

-Lugols Dosage Chart

-Nebulizing Iodine

-Required Nutrient Support

-Iodine side-effects

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