Heal Yourself At Home
(1) Clean Body's Cleaning Organs
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(3) Therapies Chart
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Grapefruit Seed Extract GSE Therapy Uses / Chart

Grapefruit Seed Extract (GSE)

-         “Medicine Chest in a Bottle”


About GSE


      Maximum strength GSE (Also known as Citricidal®) is used worldwide as a natural antibiotic, antiseptic and disinfectant to safely treat or cure numerous ailments - When compared to 30 effective antibiotics and 18 proven fungicides, GSE was proven to perform as well as any agents tested.


GSE Benefits

  Broad Spectrum germ killer

  Non toxic

  Powerful and effective

  Derived from natural sources      

  Well researched

  Long-term use has no negative side effects   

  Supplies vitamins and minerals


  Minimal short-term impact on beneficial bacteria

  Alkalizes blood





        What is Citricidal®? – Citricidal® is synthesized from the polyphenolic compounds found in grapefruit seed and pulp of certified, organically-grown grapefruit.


Originally developed by German researcher Jacob Harich (1919-1996) as an anti-parasitic agent, grapefruit seed extract (GSE) was further researched by University of Florida at Gainesville as an effective means of protecting fruits and vegetables from mold damage, who found that GSE could also inhibit growth of bacteria, mold and fungi.


Citricidal Brochure


        Note on recent comments resulting from a German study that it is added preservatives in GSE that are its active ingredients and not the GSE - 6 commercial grapefruit seed extract products were tested in this study, which determined that all 6 contained benzethonium chloride and 3 contained triclosan (a common germicide) and methylparaben  - all 3 chemicals toxic to humans. One product contained no preservatives but also demonstrated no antimicrobial activity on the microbes tested. According to the manufacturer, every batch of Citricidal® is certified for the absence of not only pesticide and herbicide residues, but also the absence of the preservatives benzethonium chloride, triclosan and methylparaben. United States Testing Company Report No. 405993, dated 9/8/95 supposedly confirms these results, but this author has been unable to locate it on the web.). The results show that without these preservatives present, Citricidal® displays very strong antimicrobial activity. Additionally, every batch of Citricidal® is tested and certified free from chemical and heavy metal contamination.


One explanation for the study’s findings is that Citricidal® has a similar molecular weight to benzethonium chloride and may have been misidentified.


Citricidal’s General Manager, Richard Perry, gave the following response to the question “Can you tell us how it is manufactured?” in an interview by a board member of the Natural Ingredient Resource Center:


“We cannot give you our proprietary process. All I am willing to offer is that we start with grapefruit bioflavonoids and convert them into a quaternary ammonium compound similar to a known, but toxic, compound called benzethonium chloride. The difference is our product has an oxygen and carbon bond that is different than that of benzethonium. Our product also has an LD50 of over 5000 mg/kg of live body weight. That means that an average weight human would have to consume a quart of CITRICIDAL daily before there would be a 50% chance of death as a result. Our product is used by the drop”.


Citricidal has been used worldwide for over three decades with no reports of it having caused harm to anyone and yet there are thousands of both clinical and anecdotal reports of how it has helped people with many microbially related health issues. Bottom line - you will need to come to your own conclusion on this.


How GSE is made and its active ingredients



        When used at appropriate doses, no other known antibiotic exhibits such safety and versatility - GSE is highly active against many disease-causing pathogens, including protozoa, bacteria, yeast and some viruses. GSE can be administered for up to several months, which may be necessary for some stubborn, chronic infections. GSE is also being used to benefit pets and animals of all sizes. Its uses are only limited by ones imagination. 


        Relative Potency of Anti-Microbial Agents - This Minimum Inhibitory Concentration Study was used to evaluate the relative potency of Citricidal® compared to other antimicrobial agents. It demonstrates Citricidal® to be a minimum of ten times(10X) to one hundred times (100X) more effective than other agents tested against the organisms used in this study.



Effectiveness of GSE Compared to other Biocides


      GSE shown effective in treating hundreds of different microorganisms organisms



Bacteria (both gram-negative and gram-positive) including Campylobacter jejuni, Chlamydia trachomatis (obligate intracellular bacteria), Escherichia coli,  Haemophilus influenzae, Klebsiella, Mycobacterium species, Pseudomonas aeruginosa, Salmonella, Shigella, Staphylococcus, Streptococcus pneumonia, Proteus, Vibio cholerae, Legionella pneumophila, Helicobacter pylori


Viruses - Herpes simplex 1, Influenza A2, and measles virus


Fungi/Yeasts – Aspergillus niger, Aspergillus fumigatus, Candida albicans, Epidermophyton floccosum, Keritinomyces ajelloi, Monilia albicans, Saccharomyces cerevisiae, Trichophyton mentagrophytes, Trichophyton rubrum, Trichophyton tonsuran 


Parasites/Protozoa - Entamoeba histolytica, Giardia lamblia, Trichomonas vaginalis




      How Does GSE Destroy Bacteria? - using Scanning Transmission Electron Microscopy (STEM) it was evident that GSE disrupts the bacterial cell membrane, releasing its cytoplasmic contents within 15 minutes of contact. At 1:256 dilution GSE is bactericidal and toxic, but at 1: >512 dilution GSE is bactericidal, but also completely nontoxic.

Heggers JP et al, The Effectiveness of Processed Grapefruit-Seed Extract as An Antibacterial Agent: II. Mechanism of Action and In Vitro Toxicity, J. of Alternative and Complementary Medicine, 2002.


      Does GSE harm beneficial intestinal flora in the intestines? - One study found that GSE significantly inhibited E. coli (a normal inhabitant of the GI tract), but left the important and beneficial Bifidobacteria  unchanged, and only slightly reduced the Lactobacilli  species. The conclusion is that typically recommended doses of GSE do not significantly affect intestinal and urogenital flora, while massive GSE doses are likely to compromise beneficial flora. GSE may actually assist the growth of the beneficial bacteria by inhibiting pathogenic microbes which compete with the beneficial flora.

The Healing Power of Grapefruit Seed by Shalila Sharamon and Bodo J. Baginski.

The Authoritative Guide to Grapefruit Seed Extract, by Allan Sachs, D.C. C.C.N


      If used long-term, it may be necessary to take a Probiotic with GSE - just as synthetic antibiotics can kill off the naturally occurring flora in the body, so might GSE if it is used long-term in the treatment of a chronic infection, in which case it may be necessary to take a good probiotic supplement.

Take GSE between meals, and probiotics 20-30 minutes before meals - As with anything, consistency and persistence are the keys to success.


      GSE is used against Immunodeficiency related diseases - to defend against fungi, bacteria, viruses, parasites or secondary infections that are common in those suffering from immunodeficiency diseases such as HIV positive (Aids) and Chronic fatigue syndrome.  GSE’s broad spectrum anti-pathogenic activity relieves the immune system of an enormous burden.


      GSE is successfully used against Mold and Yeast Fungus -  which are just as disease-causing as bacteria and viruses. An estimated 50% of those who are sick have some type of fungal disease. Fungal diseases in the body are more likely with an impaired immune system, which is caused partly by overuse of strong antibiotics and CORTISONE, stress, environmental toxins, unbalanced or insufficient nutrition, food additives, steroids, birth control pills, chlorinated water, etc., which provide an opportunity for fungal growth by offsetting the natural balance of intestinal bacteria. Molds and yeast fungi assist in the development of cardiovascular disease, rheumatism, arthritis, gout, asthma, allergies, sinusitis, gastritis, tuberculosis, cancer, and more.


      Avoid mycotoxins - Mold fungi by-products produce some of the strongest poisons known, called mycotoxins. Many of these molds can be found in food or damp musty areas.


If sick, you should avoid foods containing mycotoxins - which can further weaken your immune system and actually feed Candida Albicans. In Germany, it is estimated that 7-12 thousand people die annually of fungal infections.

Some of the more common mycotoxins include:


-       Aflatoxin - one of the most potent carcinogens known; in beer, peanuts, brazil nuts, bulk grains, bread more than a few days old and overripe fruit. A large dose of aflatoxin can debilitate the liver for years, reducing it's ability to detoxify.


-       Patulin - deadly mycotoxin associated with cancer; in overripe apples and other overripe fruit


-       Zearalenone - a corn mold which occurs in brown rice, popcorn and corn chips.


-       Ergot - associated with cancer and occurs in whole grain products, processed honey and alcoholic beverages.


      GSE is one of the best non-toxic remedies for Candida - According to worldwide reports from holistic physicians and thousands of their patients. In addition, GSE can simultaneously detoxify the system of other fungi, bacteria and parasites that often go hand-in-hand with Candida.                



  CANDIDIASIS - Candida Albicans/Yeast Infection


      Can germs become resistant to Grapefruit Seed Extract as they can to antibiotics?
There is no evidence that any type of microorganism has ever developed a resistance to Citricidal®.


      How long can I safely take grapefruit extract? - You can safely take GSE over a long period, if needed, without any worry of toxicity. People have taken GSE every day for years (as a preventative) without side-effects of any kind. An example of a need for long-term use is for a long- standing parasite infection, which could take quite some time to overcome.


      Does GSE interfere with High Blood Pressure Medication? - There are no reports of any drug interactions or contraindications of any kind. Drinking fresh grapefruit juice or eating grapefruits when taking certain medications has increased medication absorption, but GSE contains 0.1% or less of the compounds that cause this phenomenon. 





Therapies Chart

  1-2-3-4 Therapy Plan

  Herxheimer Reaction

  Timing is of the Essence


Grapefruit Seed Extract (GSE) LINKS



About Grapefruit Seed Extract (GSE)

-  Available forms of GSE


About Taking / Using GSE

-  WARNINGS  for Using GSE

-  Human Uses

-  Household /Miscellaneous Uses

-  Horticultural uses

-  Pets, Animals, Birds and Livestock Uses

DISCLAIMER - The information given at this website is for research purposes only. It is not intended to diagnose or cure any mental or physical condition. It is not intended as a substitute for the advice of a licensed professional. In the event that you use this information for your own health, you are prescribing for yourself, which is your constitutional right as a U.S. citizen under Amendment IX of the U.S. Constitution, and for which the author of this information assumes no responsibility. The author of this information is neither a legal counselor nor a health practitioner and makes no claim in this regard. Any references to health benefits of specifically named products on this site are given as this website author's sole opinion and are not approved or supported in any manner by their manufacturers or distributors. COPYRIGHT 2009-2017