Heal Yourself At Home
Estrogen Dominance Main

Estrogen Dominance (ED)



The term “Estrogen Dominance”was coined by Dr. John R. Lee, an author, expert and pioneer in the study and use of PROGESTERONE and androgen supplementation to restore hormonal balance.


Estrogen dominance (ED) refers to a condition in the body where estrogen presence is out of balance with (i.e. unopposed by) other hormones - ED encompasses several unpleasant symptoms and maladies including:

✔ Anxiety, mood swings, confusion, depression, irritability;

✔ Tiredness;

✔ Headaches;

✔ Fluid Retention;

✔ Breast Tenderness, FDB, endometriosis, ovarian cysts, BPH, reproductive organ cancers (e.g. breast, ovarian, endometrial, prostate);

✔ Weight Gain

What is causing ED?

–    ED can be caused either by excessive intake or production of estrogen or insufficient intake or production of other hormones, such as TESTOSTERONE and PROGESTERONE - It is important to grasp the concept that it is not so much the actual levels of hormones in the body, so much as their levels relative to other hormones present.

–   ED is commonly seen in women as they progress through menopause and beyond - since PROGESTERONE levels drop more drastically than estrogen levels, creating a relative imbalance favoring estrogen. Also, a vicious cycle presents, whereby ED promotes fat storage, and fat cells produce more estrogen.

–   In aging men, estrogen levels increase /TESTOSTERONE and PROGESTERONE levels decrease - as TESTOSTERONE levels generally decline with age, and the often increasing number of fat cells convert TESTOSTERONE to estrogen. Also weak testes produce less PROGESTERONE

–   Without ovulation, there is no ovarian corpus luteum to produce PROGESTERONE, and a PROGESTERONE deficiency ensues - Any estrogen present remains unopposed, yielding several unwantedside effects. Unfortunately, maladies such as water retention, weight gain, fatigue and depression are sometimes diagnosed as separate problems and treated individually, when actually, they are symptoms of a person with too much estrogen relative to other hormones.

Today, research is showing that many women in their 30s and even younger are sometimes not ovulating during their menstrual cycle.

Lee, John R., M.D., Natural PROGESTERONE: The Multiple Role of a Remarkable Hormone, BLL Publishing, California, USA, 1993, p.29.1

Those of us living in the developed world are “bathed in a continuous sea”of estrogen and are all likely facing hormonal imbalances resulting in estrogen dominance - A few of the reasons why ED is becoming so commonplace in both women and men are listed below, but for more detailed information:

ED –Why so prevalent?

For guidance in restoring the body's normal healthy hormonal balance:

ED - Solutions


Interview with Dr. Lee http://www.keepsmilin.com/transcriptdrlee.htm

Estrogens - Links


Related Links:

ABOUT Estrogens


“Predominantly Female Sex Hormones”

- Production in Reproductive-age Women

- Production in Men / Post-menopausal Women

Estrogen Production Site Chart

-Estrogen Metabolism

-Activity / Concentration in Tissues

Circulating Estrogen Levels

Estrogen Elimination

Estrogen Receptors (ER-α; ER-β)

ERs and Cancer

Transport and Availability

-Symptoms of High or Low Estrogen

- Estrogens and PROGESTERONE in Lifestage Events

SPECIFIC Estrogens



-ESTRIOL (E3) –Weak / Protective

Health Benefits of Topical ESTRIOL

ESTRIOL Supplementation

- Comparative Strengths


-Health Effects in Body

-Estrogen HRT is NOT necessary

-Estrogen's Role in Fat burning and storage



- In Women

- In Men

- Estrogen and Progesterone - Yin/Yang

-Health Problems

- Why has ED become so prevalent?

- Xenoestrogens –”Endocrine Disruptors”

Xenoestrogen Chart

- Solutions to overcome ED

REDUCE Estrogen

REDUCE Estrogen levels

- DIM - Estrogen blocker with Anti-Cancer Benefits

DIM Supplementation

-Magnesium /B-Vits Aid Liver's E clearance

Hormones Links

HORMONES- Related Links:


Hormones 101 –“Feel Good, Look Good”

Chart of Human Hormones

Testing Hormone Levels

> Take Hormone Test

Synthetic Hormones

–“Frankenstein Version of Natural Hormones”

Balance Adrenal "Stress Managment" Glands


5-HTP –“SSRI Alternative”

SEROTONIN –“Mood Hormone”

MELATONIN –“Darkness Hormone”

> The Biological Clock

T3 and T4 - “Thyroid Hormones (Triiodothyronine and Thyroxine)”

HISTAMINE –“Inflammatory Response Hormone”

Fight or Flight Catecholamines:


DOPAMINE –“Go Get it! /Reward Hormone”


Low Dose Naltrexone (LDN)- “For auto immune disease, cancer, AIDS, COPD and the common cold”

FSH, LH and GnRH

PROLACTIN –“Cool Down Hormone”

INSULIN –“Blood Sugar Uptake”, GLUCAGON, IGF

LEPTIN –“Curb appetite / Burn Fat”

GHRELIN –“Hunger Hormone”


Steroid Hormones

Steroid enzymes affecting Steroid Production /Activity


CORTISOL –“Stress Hormone”



Sex Steroid Hormones

Sex Steroid Hormones

Sex hormone-binding carriers

Estrogens –“Predominantly Female Sex Hormones”



PROGESTERONE –“Precursor to Androgens, Estrogens and Corticoids”

Estrogens and PROGESTERONE in Lifestage Events

Androgens -"Predominately Males Sex Hormone"


Vitamin D - The Sunshine Vitamin

CALCITRIOL (active form)

CALCIDIOL (circulating form)