Heal Yourself At Home
Inflammation Caused by Omega-6 / Omega-3 Imbalance

Too Many Inflammatory Fats

/ NOT Enough Anti-Inflammatory Fats

- Generally not enough Omega-6 GLA  and Omega-3 EPA and DHA



The type and quantity of essential fats you eat has an effect on the body’s inflammatory response


      Certain essential fatty acids located in cell membranes produce specific “hormone-like” substances (called eicosonoids) in a cell’s immediate environment, to effect either an inflammatory or anti-inflammatory action – the most well-known of these eicosonoids are prostaglandins, leukotrienes , thromboxanes and prostacyclins;


      Omega-6 fats yield both inflammatory and anti-inflammatory eicosonoids / Omega-3 fats have only an anti-inflammatory effect     



Fats that work towards reducing inflammation


      EPA is converted by the COX and LOX enzymes to anti-inflammatory prostaglandins and leukotrienes


      Omega-3 fats in a cell membrane that contain or yield the essential fatty acid EPA:


-       Marine foods and supplements contain EPA including oily fish (E.g. salmon, herring, trout, mackerel), fish oil and Neptune krill oil (hands-down the best supplement choice);


Neptune Krill Oil (NKO)


Fish - Getting Your Omega-3 EPA / DHA by Eating Fish



-      Plant foods flax, hemp and chia seeds, and also walnuts are rich in alpha-linolenic acid (ALA) that can be converted to EPA, to yield anti-inflammatory eicosonoids via the COX and LOX enzymes - however the conversion process requires certain enzymes, which themselves need specific vitamins and minerals, which may be deficient in certain people, such as the elderly, certain races, and those who are ill;



Inhibitors of Conversion Enzymes for Omega-3 ALA and Omega-6 LA Fatty Acids


Flax SeedChia SeedHemp Seed


       Omega-6  fats that yield anti-inflammatory Series-1 prostaglandins (PGE1) from dihomo-gamma linolenic acid (DGLA)


-      Omega-6 linoleic acid (LA) found in nuts and seeds, but more often in typical grocery store oils (E.g. corn, soybean oil) and processed foods containing them - can be converted to GLA and then converted via enzymes to DGLA to yield anti-inflammatory eicosonoids; DGLA can also be derived from GLA found in high amounts in borage, evening primrose and blackcurrant oils, which are the usual supplement sources for DGLA  (which is only found in mother’s milk in any quantity); PGE-1 molecules are about 1/2 of your inflammation-fighting capability. Without them, you have a persistent tendency toward inflammation, which often leads to insulin resistance, obesity and many deadly diseases.



Fats that tend to increase inflammation


      Omega-6 AA essential fatty acids  yield inflammatory eicosonoids


-      Omega-6 arachidonic acid (AA)  - found in meat and dairy yields inflammatory prostaglandins and leukotrienes; also linoleic acid (LA) fatty acids found in typical grocery store oils and processed foods can be converted to AA


For more information on the eicosonoids, how to optimize conversion enzymes and how to ensure a healthy intake of the essential fats:


EFAs → Local “Hormones” (Eicosonoids) – “First Response Team”




Vitamins and Minerals for effective use of EFAs


Inhibitors of Conversion Enzymes for Omega-3 ALA and Omega-6 LA Fatty Acids


Enhance Omega-3 ALA conversion to EPA/DHA


Inflammation Links




- Can't Live with it, Can't Live without it!           

- Acute Inflammation 

- Chronic Low-Level Inflammation 

 Chronic Low-level Inflammation is a common factor in most health problems


 About inflammation Process

- Inflammation "Players"
- Mechanism of ACUTE inflammatory Phase

- Detailed  inflammation process 


Causes of Chronic Low-level Inflammation


Stress, Toxins, Damaged Fats, Microbes and NOT Enough Antioxidants 


Too Many Inflammatory Fats . NOT Enough ANTI-Inflammatory Fats


Too Much Sugar/HFCS and Other Refined carbohydrates   


 Too Much Meat & Dairy / NOT Enough B-Vitamins


 NOT Enough Alkaline-Forming Foods


Health Problems linked with chronic low-level inflammation



- Short-term Relief and Long-term, Natural Solutions

 - Short-Term Relief

- Long-Term Solutions