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Thyroid Disorders:

Thyroid Disorders - Autoimmune Thyroiditis - Anti-thyroid Antibodies

Autoimmune Thyroiditis - Anti-thyroid Antibodies

The anti-thyroid antibodies involved with autoimmune thyroiditis are:

•  Anti-thyroid peroxidase (TPO Ab) -  attack the thyroperoxidase enzyme (TPO), responsible for thyroid hormone production.

•  Anti-thyroglobulin (Tg Ab) -  block a protein made by the thyroid, necessary for making thyroid hormones.

•  TSH Receptor Antibody (TRAb) - stimulate thyroid hormone production by binding to Thyroid Stimulating Hormone (TSH) receptors.

 And possibly:

•  Na+/I- Symporter (NIS) Antibody - the NIS transports iodide into the thyroid follicular cell and this antibody is present in 20% of Grave's disease and 26% of Hashimoto's thyroiditis.

Saravanan P, Dayan CM (June 2001). "Thyroid autoantibodies".Endocrinol. Metab. Clin. North Am: 315-37, viii..

Thyroid damage ==> immune system anti-thyroid antibodies ==> increased or decreased TH production

Thyroid problems can develop when damage to thyroid gland components /thyroid inflammation causes the immune system to produce anti-thyroid antibodies - which can result in a malfunctioning thyroid which either  (1) DECREASES or (2) INCREASES  thyroid hormone production:

Thyroid damage / inflammation =>

(1)  Anti-thyroid antibodies TPOAb or TgAb => Reduced thyroid hormone production ▼▼▼ 

Antibody against TPO (TPOAb) - These antibodies damage the TPO enzyme responsible for adding iodine to thyroglobulin protein in TH production; usually a consequence of iodine and/or selenium deficiencies; high TPO Ab found in ~90% of patients with Hashimoto's thyroiditis.

Antibodies against thyroglobulin (TgAb) - These antibodies block thyroglobulin (Tg),a protein synthesized by the thyroid, required for making thyroid hormones (T4 and T3).High TgAb levels seen in patients with Hashimoto's thyroiditis.

-    Also, women's high level TgAb linked to Infertility/miscarriage - for currently unclear reasons, TgAb can interfere with implantation of the embryo in the uterus.

(2) TSH Receptor Antibodies (TRAb) =>Increased thyroid hormone production ▲▲▲ 

TSH Receptor Antibodies (TRAb)  - found in ~95% of those with Grave's hyperthyroidism. These antibodies stimulate thyroid hormone production by binding to thyroid stimulating hormone (TSH) receptors.

CHART OF ANTI-THYROID ANTIBODIES and Associated DISEASEs

ANTI-THYROID ANTIBODIES

ACRONYM

PRESENT IN

Anti-thyroid peroxidase (TPO) antibody

TPOAb

Autoimmune Thyroiditis (E.g. Hashimoto's thyroiditis (found in ~90% of cases), Postpartum thyroiditis)

Graves Disease (found in ~75% of cases)

Anti-thyroglobulin antibody

TgAb

Thyroid cancer; Autoimmune Thyroiditis (E.g. Hashimoto's thyroiditis, Postpartum thyroiditis)

Anti-Thyroid Stimulating Hormone (TSH) receptor antibody

TRAb

Graves Disease (found in ~95% of cases)

For more information on thyroiditis damage caused by autoimmune anti-thyroid antibodies:

Thyroid damaged by anti-thyroid antibodies - ▲Thyroid Disorders

NEWSTARTS CHART

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C-Reactive Protein - Reliable Inflammation Marker
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Inflammation

Chronic low-level inflammation (CLII) involved in almost all health problems

How to treat CLII


Pulsed Electromagnetic Field Therapy (PEMFT)

Electrotherapy

       "The medical kit of the future"

The Body Electric

General electrotherapy health benefits.   Used systemically and/or locally at specific problem areas of the body, its effective application has many benefits:

Detoxification Wellness / Healthy aging Pain relief 
Relief from insomnia Immune system restoral Anti-Inflammatory
Maximizes cellular energy production Accelerated tissue /bone
/scar healing
Stress Reduction
Muscle relaxation / rehabilitation Increased blood oxygen
/ circulation
+++

There are several reasonably affordable electrotherapy devices available for personal use. The following electrotherapies are those that have received a significant amount of positive feedback:

Cranial Electrotherapy Stimulation (CES) applies specific frequency patterns to the head area, with the following benefits:

Balances neurotransmitters Relieves pain Treats depression
Substance abuse withdrawal Relieves insomnia Relieve stress / anxiety
Anti-Inflammatory Fibromyalgia +++