Estrogen Dominance

Estrogen and PROGESTERONE - A "Yin / Yang" relationship

PROGESTERONE is essentially the "antidote" to estrogen. Men generate less estrogen than women, and so generally do not need as much of the PROGESTERONE "antidote".

ESTRADIOL is:	PROGESTERONE is:
• Inflammatory	• Anti-inflammatory
• Stimulates tissue growth	• Sloughs off tissue
• Neurostimulating	• Calming
• Immuno-supporting	• Immuno-suppressive

If estrogen levels stay unopposed by PROGESTERONE, any of several health disorders may develop. In particular, women experience many unpleasant symptoms when estrogen levels are high compared to PROGESTERONE, during menopause or the monthly menstrual cycle.

A healthy PROGESTERONE /ESTRADIOL (E2) ratio for a woman. Is~ 200-300 to 1. Breast or uterine cancer most often occurs in women with a PROGESTERONE / E2 ratio of less than 200 to 1.

A tragic illustration of the effects of estrogen without sufficient PROGESTERONE. The synthetic estrogen drug Premarin was prescribed for years to women without any accompanying PROGESTERONE, resulting in an epidemic of uterine cancer. This led to estrogen and PROGESTERONE (albeit synthetic versions with unpleasant side-effects) being prescribed in combination.

Comparison between Effects of Estrogen and PROGESTERONE
Estrogen Effects	PROGESTERONE Effects
Causes the womb lining to thicken	Causes the endometrium to shed
Increases body fat deposits	Burns body fat for energy
Triggers depression, anxiety & headaches	Acts as an anti-depressant
Stimulates breast tissue / Sore breasts	Protects breast tissue (e.g. against fibrocystic breast changes (FCC) )
Decreased libido (also with a deficiency of estrogen)	Optimizes libido/Restores normal sexy feelings
Causes salt, sugar and fluid retention	Acts as a natural diuretic
Causes breast and prostate cancer; Increases risk of endometrial/uterine cancer **	Helps prevent breast, endometrial, uterine cancer
Counteracts thyroid hormone action ***	Aids thyroid hormone action
Causes copper levels to increase/zinc to decrease	Helps to balance copper and zinc levels
Reduces oxygen supply to all cells - Estrogen shifts cells away from oxidative energy production (âž” cancer)	Corrects oxygen supply to cells
Increases risk of blood clotting	Normalizes risk of blood clots
Prolongs monthly bleed time	Normalizesperiod length
Acts as an abortive	Initiates/Sustains baby's survival throughout pregnancy
High corticosterone	Precursor of corticosterone production
Slows breaking down of bone by its rate-limiting effect on osteoclast function	Stimulates bone building by stimulating osteoblasts
Stimulates nervous system	Calms nervous system
Reduces blood vessel tone/ability to constrict or dilate
Impairs blood sugar control	Normalizes blood sugar control

** ESTRADIOL excess causes breast and prostate cancer. Newer studies show beyond debate that unopposed ESTRADIOL actually causes, not just increases the risk for breast cancer and prostate cancer.

*** Estrogen Dominance slows down metabolism causing hypothyroid symptoms, such as fat gain - The thyroid hormones T3 and T4 enter every cell in the body to stimulate protein synthesis and provide energy by utilizing calories; estrogen stores calories as fat. A surplus of estrogen triggers the liver to produce thyroid-binding globulin, which binds and neutralizes T3 and T4 in the blood. While the thyroid is producing sufficient amounts of hormone (tests are usually normal or just below normal) an insufficient amount of thyroid hormones is making it to the cells, such that an estrogen dominant person looks hypothyroid. E.g. thinning hair, low temperature, and increased fat on the hips and belly..

After 4-6 months of getting rid of xenoestrogens and phytoestrogens, and taking PROGESTERONE, the thyroid hormones are usually "back in business"

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