GSE
Kidney Failure - Baking Soda slows kidney function decline by improving rate of creatinine clearance from kidneys
Chronic
kidney disease (CKD)
Bicarbonate
dramatically slows rate of decline of kidney function in patients with CKD
Science Daily reported
results from a randomised
controlled trial lasting 2 years involving 134 people with CKD and metabolic
acidosis at Royal London Hospital in
England, that "in patients taking sodium bicarbonate, the rate of decline in
kidney function was similar to the normal age-related decline".
Metabolic acidosis
"A condition where there is an acid-alkali imbalance in the blood, that
results in high blood acidity (low pH) and low plasma bicarbonate
levels. Several conditions can lead to metabolic acidosis, including
heart failure, drugs or toxins, kidney failure or diabetic
ketoacidosis (caused by high blood sugar resulting from reduced
insulin). It is a common complication in people with advanced
chronic kidney disease, and it can interfere with protein metabolism
and may lead to stunted growth (in children) and loss of bone and
muscle."
http://www.nhs.uk/news/2009/07July/Pages/Bakingsodaforkidneypatients.aspx
People excluded from study. Anyone with morbid obesity,
cognitive impairment, chronic sepsis, congestive heart failure or uncontrolled
blood pressure.
Rate of creatinine
clearance from kidneys was assessed.
Creatinine is a waste product usually removed by healthy kidneys and is
therefore a measure of kidney disease severity. Participants provided 24-hour urine samples (collecting every drop of
urine during each period) every two months. Researchers defined rapid
progression as a reduction of creatinine clearance of more than three ml/min per
1.73m2 per year.
Study results:
Those taking sodium bicarbonate supplements had
significantly higher blood bicarbonate levels
Increased sodium levels in patients did NOT lead
to any problems with increased blood pressure
Chronic kidney disease progressed rapidly in 9%
of patients in the bicarbonate group compared to 45% in the usual care group.
Significantly fewer supplemented patients
developed end-stage renal failure
(requiring dialysis) compared to the
usual care group. 6.5% versus 33% of patients.
Supplementation was associated with better nutritional status.
Including improved protein intake and more normal
protein metabolism.
Ione de Brito-Ashurst , Mira Varagunam , Martin J. Raftery , and Muhammad M.
Yaqoob. Bicarbonate
Supplementation Slows Progression of CKD and Improves Nutritional Status. Journal of the American Society of
Nephrology, 2009; DOI:10.1681/ASN.2008111205
Dose used to slow the rate of kidney decline in
patients with CKD
Approx. 600 mgbaking soda three times daily given orally in tablet form
(increased as necessary to achieve and maintain blood levels). 600 mg is equivalent to ~ ¼ TEAspoon baking soda powder, which can be taken dissolved in a small glass of
water or juice for consumption;
For greatest effect in kidney disease,
sodium bicarbonate should always be used with magnesium chloride.
Providing
a powerfully synergistic therapy
Transdermal Magnesium Chloride
Nebulizing Magnesium Chloride
Radiation and chemotherapy both deplete the body's magnesium levels