Heal Yourself At Home
GSE C. Difficile

Clostridium difficile - An antibiotic-associated infection

Antibiotic use allows infecting C. difficile bacteria to take over intestines and wreak havoc.   Causing damage, inflammation and severe diarrhea

C. difficile is an infectious, antibiotic-resistant, toxin-producing bacteria (usually accidently ingested in a hospital, nursing home, assisted-living or similar community facility).   C. Diff overruns the normal gut flora (most often in immuno-compromised /elderly patients) after this beneficial flora has been wiped out by a broad spectrum antibiotic

C. difficile infection is sometimes misdiagnosed as Irritable Bowel Syndrome (IBS) or the stomach flu

What is C. difficile?

C. difficile is an anaerobic, gram positive, spore-forming bacillus

The overpopulating C. difficile bacteria release toxins (Toxin A and Toxin B) that damage / inflame the lining of the intestines.  Causing bloating and severe diarrhea (C. difficile-associated diarrhea / CDAD) with abdominal pain:

  The toxins destroy the normal colon cells and produce pseudomembranes.   Visualized on colonoscopy as yellowish-white plaques of inflammatory cells on the interior surface of the colon;

   Can lead to infection of the colon.   Identified as C. difficile colitis or Pseudomembranous colitis, promoting severe inflammation;The toxins destroy the normal colon cells and produce pseudomembranes - which are visualized on colonoscopy as yellowish-white plaques of inflammatory cells on the interior surface of the colon;

✔   CDAD is a major cause of morbidity, especially in the elderly.   C. difficile infections have dramatically increased in recent years, with 500,000 cases and ~15,000 deaths annually in the U.S., according to the U.S. Centers for Disease Control & Prevention. A compromised immune system and delayed diagnosis appear to be factors in an elevated risk of death;

✔   This infection is adding significantly to hospitalization costs.   Currently over $1 billion/year in the U.S.  C. difficile is acquisitioned in 13% of patients with hospital stays of up to 2 weeks, and 50% in those with hospital stays longer than 4 weeks.

Clostridia bacteria are normally found in small amounts in the small intestine ileum and colon.   It is rarely found in the oropharynx, stomach, or small intestine jejunum

side bar
DISCLAIMER: The content on this website is intended for informational, and educational purposes only and not as a substitute for the medical advice, treatment or diagnosis of a licensed health professional. The author of this website is a researcher, not a health professional, and shall in no event be held liable to any party for any direct, indirect, special, incidental, punitive or other damages arising from any use of the content of this website. Any references to health benefits of specifically named products on this site are this website author's sole opinion and are not approved or supported by their manufacturers or distributors. COPYRIGHT 2009-2019