(From germination
of intestinal spores that "escaped"standard therapy
or reinfection) |
Oral vancomycin therapy
|
Tapering Vancomycin (shown
to be effective) |
125 mg 4 times/day X 7 days;125 mg twice daily X 7 days;125 mg once
daily X 7 days;125 mg every other day X 7 days125 mg every third day
X 14 days |
|
|
Vancomycin PLUS |
125-250 mg 4 times/day X 14 days |
Rifampin |
150-300 mg twice/day X 14 days |
or Bacitracin |
25,000 U4 times/day X 14 days |
Oral Anion-binding substances
(binds C. difficile toxins) |
Anion-binding resin: Cholestyramine (LoCHOLEST, Prevalite, Questran)
slows fecal transit time but also binds C. difficile toxins (Cholestyramine
alternative: Eat a banana or banana flakes twice a day) PLUS |
4 g 3-4 times/day X 14 days (but avoid constipation)Must take medications
3 hours apart because the resin of cholestyramine can bind vancomycin |
Vancomycin |
125-250 mg 4 times/day X 14 days |
|
|
Bentonite clay or
Activated
charcoal PLUS |
See links for dosages / Avoid constipation |
Vancomycin |
125-250 mg 4 times/day X 14 days |
Oral probiotic therapy |
Saccharomyces boulardii
PLUS |
500 mg twice daily for 4 weeks |
Vancomycin (Vancocin, Vancoled) Reduced relapse
rate by 50% in randomized placebo-controlled trial - well tolerated. |
125 mg 4 times/day for 10-14 days |
|
|
Vancomycin (Vancocin, Vancoled) Then after Vancomycin course: Lactobacillus
GG (Culturelle, Lactinex) |
125 mg 4 times/day for 10-14 days100 billion organisms 4 times/day
X 7-14 days |
Continued Probiotic Therapy |
It is advisable to follow any of the above therapies by taking a
quality probiotic supplement for a month or two to restore normal GI
tract flora. E.g. Dr. Mercola® Complete Probiotics |
Minimum 50 billion CFU /day (multi-strain/high production quality)
x 30-60 days |