Thyroid Disorders:
Underactivity of thyroid tissue → underproduction of thyroid hormones to maintain body's normal metabolism
Present in Cretinism, Hashimoto's thyroiditis;
Cretinism |
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Severely stunted physical growth and mental retardation due to untreated thyroid hormone deficiency (congenital hypothyroidism) in babies or children born to women lackingiodine. - Sufficiency of maternaliodineprevents cretinism - Babies with congenital hypothyroidism can be treated at birth with supplemental iodine. |
Pituitary TSH levels rise. This is due to the negative feedback effect of low T3 and T4 thyroid hormones;
What Causes Hypothyroidism?
Hypothyroidism occurs as a consequence of several possibilities:
- Insufficient iodine for thyroid hormone production. Most common worldwide cause;
- Thyroiditis. Inflammation of thyroid cells resulting from a source of damage to thyroid tissue;
• Hashimoto's thyroiditis. Most common problem causing hypothyroidism in N. America.
• Other forms of thyroiditis having hypothyroid phases:
•Postpartum (second phase);
•Drug-induced;
•Silent;
•Sub-acute;
•Radiation-induced
•Acute infectious.
- Inborn errors of thyroid hormone synthesis. Causes congenital hypothyroidism;
- Pituitary tumors (very rare). Cause low TSH levels and thereby reduce the production of T3 and T4. This is called secondary hypothyroidism.
Symptoms of Hypothyroidism | |
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• Feeling constantly fatigued | • Aching muscles / Vague aches and pains |
• Cold hands and feet | • Weight gain without eating more |
• Coarse, dry, thinning hair | • PMS /Heavy menstrual periods / menstrual cramps |
• Dry skin | • Forgetfulness |
• Slow heartbeat | • Loss of libido |
• Mental sluggishness/”Fuzzy headed” | • Constipation |
• Depression | • Pain in thyroid gland (at front of neck) |
• Low basal temperature | • Infertility /anovulatory cycles / repeated miscarriage |
• Slowed knee-jerk reflexes |
With hypothyroidism, the ability to convert tyrosine to DOPAMINE, NOREPINEPHRINE and EPINEPHRINE is impaired. This can cause a ripple effect of symptoms, including cognitive dysfunction.
Hypothyroidism can be mistaken for an hormonal imbalance related to an excess of estrogen
Supposed hypothyroidism could actually be Estrogen Dominance
Chronic low-level inflammation (CLII) involved in almost all health problems
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