Activates skeletal muscles.
Commonly secreted at neuromuscular joints (gaps connecting motor nerves
to muscle cells) where it stimulates muscles to contract.
At non-neuromuscular junctions, typically produces
an inhibitory postsynaptic potential. i.e. the "message" doesn't
get through
ACETYLCHOLINE in life and death
situations
Ach receptors stimulated by nicotine;
Nerve gas attacks Ach system
The venom from the bite of a black widow spider causes
an excessive release of acetylcholine.
This can lead to severe muscle contractions, spasms, paralysis, and possibly death.
Arrow tips poisoned with curare blocks
transmission of acetylcholine at nerve
cell synapses, causing paralysis
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