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Antioxidants - Fighters against free radical damage
GSE
Vitamin D - Sunshine Vitamin / Antioxidant against health problems
Vitamin D Receptors (VDRs)
CALCITRIOL (active
form of D) is a steroid-like
hormone that interacts with its nuclearVDR in target tissues -
including the small intestine (to increase calcium absorption), osteoblasts in
bone (to increase bone calcium resorption) and in the renal tubular cells in the
kidneys (to increase their calcium resorption).
CALCITRIOLinduces its own destruction -
In order to rein in its own potent
calcium metabolism actions, by enhancing expression of an enzyme
(25-hydroxyvitamin D-24-hydroxylase; CYP24), which leads to its excretion in
bile (as calcitroic acid);
CALCITRIOLregulates cell growth
and maturation - by its influence on almost 3,000 genes -since most of the body's tissues and cells possess a
VDR and CALCITRIOL
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