SAMe - And other Methyl Donor Molecules

SAMe - Essential for various body functions

SAMe is essential for MELATONIN and SEROTONIN production

-   SAMe is the daytime equivalent of MELATONIN (the darkness hormone) - and like MELATONIN, it is produced under control of the master biological clock;

-   Natural synthesis of MELATONIN (and SEROTONIN) depends on adequate SAMe synthesis during the day - SAMe donates a methyl group molecule to the enzyme (hydroxyindole-O methyltransferase) that converts the acetylated form of SEROTONIN to MELATONIN;

-   At night MELATONIN ▲▲▲  / SAMe ▼▼▼  and in the day SAMe ▲▲▲  / MELATONIN ▼▼▼  - SEROTONIN is also produced at night.

Maintains effective mitochondrial function

Prevents and curtails DNA mutations during cell replication

Restores cellular membrane fluidity / cellular communication

-   Methylation puts phosphatidylcholine in cell membranes to make them pliant - in contrast to cholesterol, which makes them stiff. Stiff membranes do not transmit signals as well as pliant membranes.

-   With age, the ratio of phosphatidylcholine to cholesterol decreases causing the membrane to "harden"- increased methylation provided by SAMe enhances cell membrane function and integrity.

-   SAMe improves cellular communication between nerve cells - SAMe helps neurotransmitters deliver their messages to the receptor sites by methylating phospholipids, from which nerve cell membranes are made.