Natural PROGESTERONE inhibits Estrogenic action - PROGESTERONE decreases the target organs response to estrogen by decreasing the number of receptors the organ has for the hormone estrogen. Receptors are molecules on cells that recognize specific hormones and allow them to carry their message to the cell.
Hypothyroidism can occur because of estrogen dominance (deficiency of PROGESTERONE relative to estrogen) - estrogen dominance decreases thyroid hormone (TH) (and therefore thyroid function) by increasing production of a protein called thyroid binding globulin, which binds TH causing it to be inactive. Whereas, TH increases body's metabolism rate and causes fat calories to be turned into usable energy, estrogen causes food calories to be stored as fat (in a premenopausal woman, the body stores fat to have enough energy for a fetus if a pregnancy develops).
Hypothyroidism, which results in weight gain and a host of other symptoms, can be corrected by the presence of natural PROGESTERONE in the body.
