Oxidants are used by immune system (IS)
to “Clean House”
Certain activated IS white blood cells
(WBCs / leukocytes) produce strong oxidants**
to kill pathogens at infection
sites, and oxidize(Eliminate)toxins and abnormal
cells
For Example:
✔ Phagocytes
produce
Hydrogen Peroxide H2O2
, hydroxyl radicalOH•,
and ozone O3 to kill
bacteria and viruses.
**Oxidants are atoms or molecules which take
electrons from other molecules–in contrast to reductants which donate electrons
to oxidants.
Biooxidative therapy lends the immune system a helping hand
Biooxidative therapyprovides
active oxidants to supplement the I.S. attack
forces - similarly
dealing with microbial infection (i.e. pathogenic bacteria, viruses, fungi,
protozoa), Oxidizing toxins and
eliminating abnormal cells
The following therapies (at appropriate doses)
provide or produce physiological oxidants(mainly
reactive oxygen species (ROS):
✔ Chlorine
dioxide therapy (CDT using MMS)
✔ Ozone Therapy
✔Hydrogen
peroxide Therapy
✔ Iodine
✔ Aerobic Oxygen Therapy
✔ Hyperbaricoxygen
-100%
oxygen breathed in a hyperbaric chamber at high pressure
✔ Photodynamic Therapy (PDT) –produces
singlet oxygen
Phospholipids and
lipoproteins provide integrity to cell membranes - without which the cell is unable to survive
Reactive Oxygen Species (ROS),
such as Singlet oxygen1O2*
and
hydroxyl radical (OH• )
can oxidize
unsaturated fatty acids comprising the phospholipid layer of bacterial and body
cell membranes -
referred to as lipid peroxidation, such
oxidation
forms hydroperoxides,
which can cause irreparable damage to
membranes not protected by
antioxidant systems. There is also a synergistic effect with cellular-formed
H2O2.
Effects include:
✔
Increased membrane rigidity
✔ Decreased
activity of membrane-bound enzymes (E.g. sodium/potassiumpumps)
✔ Altered
activity of membrane receptors
✔ Altered
permeability
Reactions involving radicals occur in chain
reactions. Note in diagram above that a hydrogen is abstracted from the fatty
acid by hydroxyl radical, leaving a carbon-centered radical as part of the fatty
acid. That radical then reacts with oxygen to yield the peroxy radical, which
can then react with other fatty acids or proteins.
R. Bowen, Free Radicals and Reactive Oxygen, Colorado State University.
Link
ROS
can also directly attack membrane proteins and induce lipid-lipid, lipid-protein
and protein-protein crosslinking - all affecting membrane function.
How do oxidants eliminate pathogens, toxins and abnormal cells?
Oxygenation
effect of biooxidative therapy oxidants
stimulates immune system (IS) function –allowing the IS to be more
effective at doing its job of removing “undesireables”from the body
Anaerobic bacteria,
viruses, fungi and damaged /abnormal cells have
weak or non-existent
antioxidant
protection systems in their membranes and thus fall prey to oxidants - and are destroyed or inactivated.
– Bacteria - singlet oxygen (
1O2*) andhydroxyl radical•
(OH•
) (produced by biooxidative therapies) are known to disrupt
the bacterial cell envelope by oxidizing its structural phospholipids
and lipoproteins and forming hydroperoxides, which cause irreparable damage to membranes not protected
by antioxidant
systems.Lipid peroxidation products include
alkoxyl
and peroxyl radicals,singlet oxygen, ozonides, carbonides, carbonyls, alkanes
and alkenes.
– Fungi (E.g.Candida albicans, athlete's foot, molds, mildews, yeasts)- The mechanism of their destruction is still under discussion, but
certain oxidants are purported to
inhibit their cell growth at certain stages.
– Viruses
– oxidants damages the viral capsid and
disrupts its reproductive cycle by interrupting the virus-to-cell contact with
peroxidation. The weak enzyme coatings on cells which make them vulnerable to
invasion by viruses also make them susceptible to oxidation and elimination.
– Toxins
– oxidants
oxidize toxic chemicalsfor
elimination from the body.
– Cancer Cells
✔ Oxidants
are antineoplastic – i.e. inhibit the
growth of rapidly dividing cells
✔ Due to insufficient
catalase (CAT) and
peroxidase (GPx) antioxidantenzymes in their cell membranes, cancer cells are incapable of
effectively inactivating cell-membrane destroying
peroxides resulting from biooxidative therapy
✔ The oxygenation effect of biooxidative
therapy deters cells from becoming cancerous and boosts immune system to deal
with abnormal /cancerous cells
- One way to understand the effects of
oxidative therapies is to realize that
at appropriately controlled
concentrations,oxidants
provide a “storm”that
destroys weak structures, but leaves intact the strong, healthy
structures that are able to withstand the onslaught.Our healthy body cells have adequate antioxidant protection against this type of
“natural selection”process, whereas weak, abnormal cellsdo not, and are thus “taken out”.
✔Following
biooxidative treatment, lactate levels decrease providing evidence that cancer
cell metabolism has indeed been inhibited - due to an increased rate of
anaerobic
glycolysis, malignant cells produce more lactate than normal cells.
Antioxidants control oxidant activity to
protect healthy cells
Oxidant
activity and presence in the body is controlled by various means:
– Life-essential
metabolic and immune system oxidants
are produced only where and when they are needed
– Oxidantspreferentially neutralize one another - thus keeping their numbers down and preventing tissue damage
– Antioxidantsprotect healthy cells fromoxidantdamage -as the “burning”/oxidation
process takes place throughout the body,
antioxidantsprevent over-oxidation,
by providing a cooling or regulating system to
maintain the metabolic “temperature”at a constant level.
✔ Normal, healthy cells have
in-house
antioxidant enzyme
systems(supported
by specific dietary trace minerals) to protect
the unsaturated
fatty acids in cellular membranes from damaging
peroxidation–these enzyme systems: superoxide dismutase (SOD), catalaseS(CAT),
reductase and glutathione peroxidase (GPx)) that protect healthy lipid membranes from
oxidation, require a
sufficiency of their needed support minerals.
✔ Fat-soluble dietary
antioxidant vitamins A, D, K,E
and
CoQ-10protect fatty acids in the cell membrane
✔ Water-soluble dietary
antioxidantvitamin B'sandCprotect against oxidative
damage in watery areas - such as blood, lymph and the cell
cytosol
HOWEVER, To prevent interference with the oxidative
nature ofH2O2therapy
you should not take antioxidants within 2
hours of a bio-oxidativetreatment.
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