Body's matrix - Body's cells are electrically interconnected - Via ECM and intracellular matrix
Body's matrix - Connects cells and provides
intercellular communication network
"The body is a unit, though it is made up of many parts;
and though all its parts are many, they form one body".
- I Cor. 12:12a
"Body Talk"
A multicellular organism requires coherent and
coordinated communication between its cells to be able to synchronize cellular processes .
In living organisms, information is carried between cells via two systems:
(1) Chemical messenger system
Mainly cells sending CHEMICAL signals. E.g. hormones,
neurotransmitters, hormonal growth stimulants / inhibitors, cytokines, immune system
signals.
CARRIED VIA THE BLOODSTREAM. Chemicals dock at receptor sites on recipient
cell membranes enabling the cell to pick up distant chemical signals.LOCALLY GENERATED CHEMICAL
SIGNALS. Eg. prostaglandins generated by immune cells,
cytokines.
Neurotransmitters are secreted across the gap
between neurons (called the synapse) to trigger receiving neurons to transmit
their specific message from the neuron's receiving dendrites to its sending axon terminals.
It does this by creating a so called "action potential" - an electrical pulse which
travels the length of the neuron - like a current down a wire.
(2) Electrical network - body's interconnected
web (MATRIX) of electrical circuits
Almost all the body's components are linked together:
a NUCLEAR matrix within an INTERCELLULAR matrix within an EXTRACELLULAR connective
tissue matrix
The NUCLEAR matrix.
The nuclear matrix is a network of fibers in the nucleus.
These fibers link the cell's genetic
components in the nucleus to the nuclear membrane.
The INTERCELLULAR matrix
The intercellular matrix (or Cytoskeleton)
is the
cell's scaffold . It
transmits electrical messages inside
cells from the cell membrane to the organelles,
continuing through the nuclear
membrane to make contact with the chromosomes.
The cytoskeleton organizes and maintains the
cell's shape and anchors organelles and enzymes in place. The cell interior (the
cytoplasm) is virtually filled with fibers, tubes and filaments, collectively called
the intercellular matrix.
The intercellular matrix has 3 types of struts:
Microtubules.
Largely composed of the protein tubulin , can become rigid to determine cell
shape; electrically energetic polarity serves to direct vesicles/motor proteins
using them as tracts; bidirectional intracellular highways.Actin filaments .
7nm diameter, composed of protein actin (as found in muscle cells); ability
to contract and relax allows cytoskeleton to change shape; contains its own ATP
(energy source),
making it independent of mitochondria; Intermediate filaments.
10 nm diameter, form wavy bundles that traverse the cytoplasm, connecting
nucleus to and suspending it away from internal plasma membrane. (Epithelial cells
contain intermediate filaments made largely of keratin ; fibroblast's intermediate
filaments are made mostly of vimentin ; muscle cell intermediate filaments
are mostly comprised of desnin .)
These continuous connections link the cell membrane
to the organelles - including a connection through the nuclear
membrane to the chromosomes.
The enzymes of the cell are attached to this cytoskeleton
Scientists now realize that cell membrane receptors also function
as antennae able to pick-up specific energy frequencies.
Using the body's electrical matrix, each and
every cell (and their components) are able to convey and receive vibratory
information to and from other cells. Energy therapies are able to restore
and reinforce this vibratory circuitry, which may be impaired by physical
and/or emotional trauma and cause the immune system repair systems to
falter.
The EXTRACELLULAR Matrix
The extracellular matrix (ECM) is a network of body tissue "cables"
lying outside the cells. The existence
of an extracellular communication network is only more recently gaining recognition
in Western medical understanding, some even referring to it as an unrecognized
organ
Provides
support and attachment for cells inside organs Provides
a communication pathway between all body cells. It also
links into nearly every cell, via The
INTERCELLULAR Matrix and the NUCLEAR Matrix.
ECM connects to Intercellular Matrix via Protein Polymers
Information is carried through the ECM by very weak electromagnetic
fields via their frequency and amplitude fluctuations. The Chinese
have known of this network for about 5,000 years, calling the energy which travels
along it our life-force or Chi (Qi). In 1994, this network (also called a meridian
system) was able to be mapped accurately using high-tech instruments now available,
capable of measuring minute amounts of electricity.
Where is the ECM?
Situated between the cell membranes and the nearby nutrient-carrying
blood vessels, the ECM is a network of connective tissue, which provides
strength, fills spaces between cells, binds cells and tissues together and links
almost every cell in the body.
ECM is plentiful in various connective tissues.
Tendons, dermis (tough/flexible), bone (hard/dense), cartilage
(resilient), jelly in eye interior (soft/transparent).
The ECM consists mostly of:
Interweaving glycoproteins bound to water to form a gel. Glycoproteins are complex chains
of sugar molecules joined to protein. E.g. Fibronectin,
laminin ,
thrombospondin, proteoglycans . Fibroblasts and fibrocytes. The main cells that produce the proteins and ground substance of the ECM in
soft tissue.
LAMININ
Laminin (also called the "basement
membrane") is a "Cross-shaped" cell ADHESION
protein molecule that holds our body together
Laminin anchors organs to itself, forming sheets of protein that
form the substrate of all internal organs. It has 4 arms in the shape
of a cross - the three shorter arms are particularly good at binding
to other laminin molecules, which is what enables it to form sheets.
The long arm is capable of binding to cells, which helps anchor the
actual organs to the membrane.
He (Christ) is before all things and IN HIM ALL THINGS HOLD TOGETHER."
- Colossians 1:17
Embedded in the glycoprotein gel are various protein polymers
Protein Polymers
Collagen. Has great tensile
strength, main component of fascia, cartilage, ligaments, tendons, bones, teeth.
Together with keratin, it is responsible for skin strength/elasticity, reduces age-related
wrinkles. Strengthens blood vessels, preventing need for repairing plaque.
Elastin. Tough fibers
provide structural support and tissue elasticity, which allows body tissues to resume
their original shape after stretching or contracting. Elastin is abundant in arteries,
especially aorta, lungs, elastic ligaments, skin, bladder, and elastic cartilage.
Fibronectin. Binds ECM
proteins to each other and to integral membrane proteins (IMPs or integrins), which
extend across the cell membrane linking the Intercellular Matrix (the matrix inside
the cell) with the ECM.
Hylauronic Acid.
Provides lubrication of tissues.
The ECM acts as a molecular sieve between the capillaries
(smallest of the blood vessels) and the cells.
Substances are diffused between capillaries and ECM. E.g.
Oxygen is transferred
from capillaries to ECM and carbon dioxide is transferred from ECM to capillaries.
The ECM is a transit and storage area for nutrients,
water and waste
A transit
area. For nutrients from the bloodstream
into the cells, for toxins released by the cells
to the bloodstream and for immune cells moving out of the bloodstream. These immune
cells are involved in inflammatory reactions by secreting cytokines and digesting
old worn out cells. They may also facilitate healing by carrying and delivering
components from other areas of the body to the cell membrane. These migrating immune
cells, as well as fixed cells in the ECM, regulate cellular functions by secreting
growth factors and cell growth. A storage
reservoir. For water, nutrients and toxins A pH buffering
system. Where the proteins of the ECM buffer acids released by the
cells.
Edema toxifies the ECM
In healthy Most of the water
in the ECM is bound as a gel, creating a physical barrier that controls an evenly
distributed fluid flow from venule end of capillaries to cells. When conditions
create edema in the ECM. Fluid flows more easily from leaky
capillaries, but these large flows of fluid are unevenly distributed, which interferes
with nutrient delivery, oxygen perfusion and waste disposal. In edematous conditions
the ECM becomes more hypoxic, more acidic and electrically more resistant.Bioflavonoids
are some of the most effective nutrients in reducing capillary leakage, which helps
reduce edema. Improves the electrical conductivity of the
ECM.
Cell Growth Control.
ECM is involved in regulating cell growth control.
Cellular
components of the ECM. Components involved in the local production
of growth factors, growth inhibitors and cytokines, which affect the growth and
metabolic activity of tissue/organ cells. Immune
cells. E.g. leukocytes, lymphocytes and macrophages
that migrate into the ECM are involved in initiating the removal of old and damaged
cells and in stimulating the growth of new cells.
Details on the Matrix Connections
Glycocalyx:
Oligosaccharide side chains attached to membrane glycolipids
and glycoproteins
The glycocalyx. Composed of negatively
charged sialic acid molecules that cap the tips of glycoproteins and glycolipids
that extend outward from the cell membrane like tree branches.
The glycocalyx
(sugar cell coat) is produced by the cells of parenchymal
organs and secreted onto their cell surfaces The ECM
and the glycocalyx work together to regulate information transfer to and from tissue/organ
cells. Accomplished by electrical field fluctuations
leading to electroconformational coupling and by soluble signaling molecules.
