Skin cancers - Basal Cell Carcinoma, squamous cell and melanoma
Skin cancer
Skin cancer can occur anywhere on the body, but
most commonly occurs in skin often exposed to sunlight. E.g. the face,
neck, and hands. It especially occurs in fair-skinned and fair-haired people, those
who had freckles as a child and those who have blue eyes.
Excessive UV-B
exposure from sunlight causes all three skin cancer types.
Excessive UV-A
exposure from sunlight now known to cause damage to proteins
and lipids and DNA lesions - by indirect (and possibly direct mechanisms), leading
to carcinogenesis (Including cutaneous malignant melanoma) and aging skin.
Link
Types of skin cancer
There are 3 main types of skin cancer, which all begin
in the epidermis:
Basal call carcinoma (BCC)
Basal cell carcinoma is the most common type of cancer in the U.S. and the most common
skin cancer . BCC is usually benign i.e.
a relatively harmless skin cancer.
Round basal cells reside under the squamous
cells. Typically looks like a red patch, scar, shiny bump, pink growth or
an open sore, which can bleed, ooze or crust. Rarely
spreads or metastasizes, but should not be ignored since it is more easily treated
whilst small.
Squamous cell carcinoma (SCC)
Flat squamous cells form the outermost
layer of the epidermis. Squamous cell carcinoma (SCC), a.k.a. "rat-bite"
tumor, is diagnosed when these cells become abnormal and grow out of control. SCC
sometimes develops from a precancerous skin growth called an actinic keratosis. SCC
is usually seen as scaly red patches or open sores, which may crust and bleed. Characteristically
it looks elevated with a central hole. Allowed to grow,
it can be fatal.
Bowens disease is a form of squamous cell cancer
in situ.
Cutaneous malignant melanoma
Unrepaired DNA damages skin cells triggering mutations, causing skin cells
to multiply rapidly and form malignant tumors. Curable if detected early,
but each year in the U.S. ~10,000 people die of this type of cancer.
In the lower epidermis, melanocytes produce melanin, the pigment that gives
skin its color. Exposed to the sun, melanocyes make more pigment causing skin to
darken.
These are the signs to look for when examining tumors,
which may indicate melanoma:
Asymmetrical: a line drawn
through the middle of a tumor produces relatively similar halves;
Border: irregular or jagged,
not smooth or ragged
Multicolored: A combination
of colors is usual, one color tumors are probably OK
Diameter > 1/4 inch:
non-malignant skin cancers tend to be smaller
Evolving: Changes in elevation,
size, color, crusting, bleeding, itching, or anything else
Topical eggplant extract.
Used since 1825, eggplant extract has been shown to be effective in
the treatment of both malignant and benign human skin tumours. Solasodine rhamnosyl
glycosides (BEC) can be extracted from eggplants. A preparation (Curaderm™)
which contains 0.005% BEC is effective in the treatment of keratoses, basal
cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) of human skin.
Link
Topical myrrh and frankincense
essential oils. DIluted in carrier oil and rubbed on lesions shown
effective against skin cancers. Myrrh is rich in sesquiterpenoid and curzerene.
Frankincense has several active ingredients. Link
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