Heal Yourself At Home


(2) Eliminate Cancer Cell


This potent therapy poisons and kills cancer cells but does not harm healthy cells

Oleander is considered a potent Stage IV cancer treatment, but NOT when the patient has less than a month to live. (Instead choose the BUDWIG /PLASMA+ Protocol or CESIUM CHLORIDE /DMSO+ Protocol, which act very quickly). Anecdotal reports inform of its positive effects against more advanced, aggressive and difficult cancers, such as leiomyosarcoma and Ewing's sarcoma.

Protocol Overview and History

Oleander Extract is indicated as both a primary and adjuvant therapy for cell proliferative disease (cancer), certain viral disease, and autoimmune /inflammatory disease - having both a strong cytotoxic and immunomodulatory effect - clinical application of ANVIRZELTM (a patented extract of oleander) in the U.S., Ireland, and Honduras have demonstrated efficacy against various neoplastic disease, hepatic disease such as Hepatitis C, late and early stage HIV/AIDS, as well as autoimmune/inflammatory disease, such as rheumatoid arthritis and psoriasis.

Oleander has been used for medicinal purposes for more than 2000 years - more recently during the 1960's, Dr. Huseyin Ozel, head of the surgical department of Mugla State Hospital in Turkey,experimented with its extract to help cure his pet dog, he subsequently used it to successfully treat cancer in people for more than 35 years . He eventually patented an aqueous extract of Nerium Oleander as ANVIRZEL™(US patent#5,135,745).

In late 1999, reports spread that Anvirzel™ reversed AIDS (regardless of the phase of the disease), arthritis, psoriasis, hepatitis C, and cancer (Anvirzel reportedly showed positive results for late stage cancers and even leiomyosarcoma, a cancer normally having a poor prognosis).

–   It is now illegal to sell or ship oleander supplements within the U.S. - Unfortunately, since Doctor Ozel had claimed that oleander was a cure for cancer, not just a natural supplement, and since his extract was patented and given a trademark, the FDA now considers oleander as an unproven medicine which, because of the toxicity of the raw plant, must have it's safety and effectiveness proven before the FDA will allow it's use even as a herbal supplement.

The costly three-phase FDA trial approval process for Anvirzel ™was begun by the Anvirzel company. The Phase I trial found Anvirzel to be safe, but lack of funding for Ozel prevented Phase II trials. Phoenix Biotech has obtained a patent for Anvirzel™ in Honduras and has also applied for a U.S. patent to make a pill form of oleander extract that is much more potent than Anvirzel™.

Phoenix Biotech established a clinic in Mexico, called Salud Integral, which hassuccessfully treated a number of patients for several years and is the source of most clinical trials (they have spent millions of dollars testing and giving away their products to dying cancer patients). Many patients travel from the U.S. both for treatment for various disorders and to purchase three month supplies of injectable Anvirzel™(very expensive). Phoenix Biotech's president says that his intent is to eventually sell the productto a pharmaceutical company, since they are the only ones big enough to play the FDA approval “game”

Another company, Shimoda Atlantic Oncology Biosciences claimed to have developed its own stronger version of oleander extract named Xenavex™using an ethanol extraction method, which increased the cardiosides and reduced the polysaccharides. This was exposed as a fraud by Tony Isaacs, since they were actually using "serio neriolini" imported from Russia, which was formulated to treat heart conditions and not cell proliferative disease.

The Minnnesota Wellness site provides more detailed information on Anvirzal's current status:


–   Two solid S. African companies are now selling an effective and affordable Nerium Oleander extract by mail – available as both capsules and a liquid extract

Benefical Health Effects of Nerium Oleander

Effectively lessens ALL known side effects of radiation and chemotherapy (except hair loss when using Cisplatin drug)- excellent adjunct treatment to chemotherapy and radiation

Nerium Oleander's effects on cancer and other diseases are multifold:

✔ Strong immune system booster

✔ Inhibition of angiogenesis

✔ Inhibition of the NF-kB factor in cancer cells

✔ Induction of apoptosis (normal cell death) in cancer cells

✔ Induction and enhancement of autophagic cancer cell death (tested against pancreatic cancer cells)

✔ Crosses the blood-brain barrier –relevant in a brain cancer protocol

Active Components of Nerium Oleander Extract (NOE)

Mechanism of Action for cytotoxic and immunological activities of oleander extract

"It is thought that the polysaccharides present in ANVIRZELTM are capable of activating the immune cells, which in turn can recognize the epitopes present on the cancer cell surfaces, thereby enhancing the efficacy of the immune response. It is believed that the cytotoxic action present in the extract may be essential for synergistic activities. It is believed that the cytotoxic action both arrests tumor growth and prevents cancer cell reproduction as well as having and/or producing a Tumor Necrosis Factor like activity.

It is essential that all the constituents in ANVIRZELTM be administered to invoke a synergistic effect on the stimulation of the immune system."

- Statement from M.D. Anderson Cancer Center

Tumor Necrosis Factor Liberation Tests have been conducted according to Stimpel, et al on ANVIRZELTM, and the results are preserved in the company files. Continuing research has proved conclusively that AnvirzelTM is active on dual pathways at the cellular level to both inhibit the growth of tumor cells and to promote apoptosis of the tumor cells.

Nerium Oleander Extract contains at least five polysaccharides, two "digitalis-like"cardioglycosides (oleandrin and oleandrigenin), and five proteins – it has not yet been determined how thay work together against sick (cancerous) cells, but the result is that the immune system function is boosted, sick cells are eliminated and healthy cells are left intact. Ozel's research showed a 70% success rate against cancer in patients who had not undergone chemo, and about 30% for those who had (realizing that oleander was likely being used as a last resort therapy in extrmely sick patients)

Active components work synergistically

ANVIRZELTM Cytotoxic Agent for Cell Proliferative Disease (Cancer) / Immunomodulatory Agent for Immune Disorders Online Link

“In 1974, he [Dr. Ozel] published additional case reports in the Turkish Medical Journal "Dirim". Doctor Ozel resigned from his position as Chief Doctor at Mugla State Hospital that same year in order to be able to work on NOE and initiate research on the subject, Doctor Ozel contacted various universities in Istanbul. Years passed and he realized that no serious scientific research could be performed in any of the local universities. In the meantime, his old patients referred new ones to him, and more cancer patients presented to him as word of the results of the treatment spread.

In 1985 he started to look for research facilities abroad. During 1986-1987 some tests performed in Europe proved the effect of NOE on the immune system as well as cancer tumors. The studies showed that it was at least six times as potent as the most active commercially available immune-stimulants (Schizophylan, Krestin and Lentinan, which were patented by the Japanese in the 1980s).

In 1988, a research team was formed at Munich University Pharmacology Institute to isolate the active components contained in the N.O. extract. Several polysaccharides were identified that might be responsible for some part of the immune activity. On 17-22 July 1990, the initial results were presented as a poster at the symposium of Biology and Chemistry of Active Natural Substances (BACANS) which was held in Bonn, Germany. The presentation was published in Planta Medica 1990-56:66. However, no single component of the extract was found to be the sole source of its benefits. Instead, the activity is induced by a complex mixture of components contained in the extract, acting synergistically to modulate the immune system.

- Tony Isaccs

Disabled World News (2008-07-20) - Will the deadly oleander plant be a future cure for cancer and leukemia: http://www.disabled-world.com/health/cancer/treatment/oleander-cancer-cure.php#ixzz2L4aU5xKX

For available information on clinical trials using Anvirzel™:

Clinical trials using Anvirzel™

Where to purchase Nerium Oleander products

OPC stands for Oleander Pure Concentrate

Oleander pills or its extract are available out of S. Africa for purchase in the U.S. and are a safer choice than making oleander soup (see Oleander Soup Recipe if this is your only option). Prices as of Feb 2013. Typical daily dose for cancer is 4-6 capsules (equivalent to 20-30 ml liquid) /day. See: Dosages for Cancer

–   Capsules

✔  Rose Laurel OPC Plus (sold by www.utopiasilver.com) – 90 capsules (oleander concentrate) ($75)

Order perks: Try using the discount code of LR001 to get:

15% off the price

A free botlle of Utopia Silver's Advanced Colloidal Silver for each $100 spent(you have to request the free bottle by phone or on your order notes).

Reduced shipping time within the U.S. from S. Africa - from the normal 10-12 days to only 3-4 days via inexpensive first class postage.

✔  OPC Plus(sold by SutherlandiaOPC.com) –90 capsules (100mg oleander extract) $70 (i.e. 22 days @ 4 caps/day)

–   Liquid

✔ Sutherlandia OPC -200 ml liquid concentrate; 80% Oleander extract (100mg) / 20% Sutherlandia Extract (called “Cancer Bush”in S. Africa) $60(i.e. 10 days @ 20ml/day)

How to take Nerium Oleander

Simple to administer – patient would not know that they are taking a potent therapy.
For details of protocol and its Yahoo discussion group:

Tony Isaacs Oleander Protocol

The Tony Isaacs (TI) oleanderprotocol includes products to support the immune system, the non-cancerous cells and the body's organs these are detailed at utopiasilver.com, but the important ones are (the first 4 are included in the “+Cancer TREATMENT CORE”) :

✔ Magnesium (400mg) – aids glutathione synthesis and ATP energy production

✔ Lugol's Iodine (5-6 drops / day)

✔ Vitamin D3 – preferably from 30-45 minutes/day bared off in the mid-day sun

✔ Selenium (200μg - eat a few brazil nuts each day) –needed for glutathione synthesis

✔ A glutathione booster – the TI protocol includes N-Acetyl Cysteine (NAC) as a precursor to glutathione (the body's powerful, primary antioxidant in the cell cytosol). However, this author is not convinced that NAC is the best way to increase the body's glutathione production (high NACdoses can lead to loss of zinc, copper and trace minerals, requiring replacement supplements), and instead, therefore suggests supplementing with quality raw, grass-fed whey protein (the TI protocol actually suggests consuming raw whey as a protein alternative)

✔ Alpha Lipoic Acid (ALA) - aids glutathione synthesis; cofactor in ATP energy production

✔ Anti-microbial suppplement – E.g. colloidal silver, grapefruit seed extract

Tony Isaacs recommends using a liquid extract in certain situations, since it can be taken sublingually or rectally to bypass the stomach (and digestive process) –this is particularly advantageous with malabsorption problems or with rectal or liver cancer.

–   Sublingual delivery – goes first to the heart and then is distributed to the blood stream; swallow liquid after holding it under your tongue for a few minutes.

–   Rectal delivery – goes first to the liver and then on to the heart to be distributed to the blood stream, thus provides an ideal route for liver or rectal cancer; administer via a rectal syringe or therapeutic enema

If the following conditions apply, consult your physician before taking OPC:

–   If taking blood thinners - because of OPC's blood-thinning properties

–   If on heart-active drugs (E.g. digoxin (Lanoxin®)) or anti-arrhythmics

No other drug interactions have been reported

–   If pregnant – pregnant women preferably should not use OPC, due to its anti-angiogenesis effect

Dosages for Cancer(information from Tony Isaacs posts on Curezone.com)

–   Dosage is obviously weight-dependent - MAXIMUM therapeutic doseage for the OPC Plus capsules for 150 # or more person is 8-10 per day.A 130# person's maximum would be about 7-9 per day

–   Dosage should always be taken WITH meals

1 tsp. (5ml) liquid = 1 Capsule

(both contain identical active ingredients)

–   Suggested protocol by OPC researchers (for Cancer, Hep C, and Neurological problems) - the idea is to work up gradually to an effective dose allowing the bodytime to adjust to the common side-effects

(1) Start by taking 1 capsule with breakfast for 2 days (with bromelain for better assimilation)

(2) Increase dosage to 1 capsule twice per day (2caps total) with breakfast and lunch for a further 2 days.

(3) For cancer (and other serious ailments / immune disorders) increase dosage to 2 capsules twice per day (4 caps total) with breakfast and lunch for 1 month.

(4) If no improvement, increase dosage to 3 capsules twice per day (6 caps total) with breakfast and lunch for 2 months.

When in remission, the dosage can be reduced to 2 capsules per day for at least a further 3 - 6 months

(from utopiasilver.com)


According to the OPC manufacturer, no reports of toxicity have been received from clinicians supervising patients experiencing Oleander Extract Therapy - Although oleander leaves and stems are toxic in their raw form, the toxic oils have been extracted leaving the pure concentrate. Supplementation as suggested with this herb seldom if ever exhibits any severe adverse side effects, but they are possible.

Possible Side Effects

Side effects of OPC can include:

✔ Slight nausea and rarely vomiting (if so, reduce or discontinue dose)

✔ Diarrhea

✔ Pruritus (itching)

✔ Pain at a tumor site

✔ Tachycardia and heart arrhythmias

✔ Blood thinning

Short-term detoxification symptoms

✔ Slight rash

✔ Runny nose

✔ Pimples

✔ Slightly painful joints

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