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Magnesium is an Anti-inflammatory Agent

Mg ▲ Inflammation ▼ 

Mg deficiency raises CRP(inflammatory marker)

o King DE, Mainous AG 3rd, Geesey ME, Woolson RF. Dietary magnesium and C-reactive protein levels. J Am Coll Nutr. 2005 Jun;24(3):166-71.

Mg (also B6 and zinc) required for the △ 6D enzyme –which convert essential fatty acids in foods into needed active forms, and which eventually convert to inflammation-controlling prostaglandins and leukotrienes (local “Hormones”called eicosonoids)

Local "Hormones"

Mg intake ▲  Inflammation ▼ 

A study by Dr. Ka He of the University of North Carolina at Chapel Hill and colleagues found a connection between dietary magnesium and a lowered risk of diabetes/decreasing INSULIN resistance - also revealed that as magnesium intake increased, inflammation levels decreased

Dae Jung Kim et al, Magnesium Intake in Relation to Systemic Inflammation, Insulin Resistance, and the Incidence of Diabetes. Diabetes Care, publ. inline Aug 31, 2011

–   “Conclusion: Our results suggest that magnesium intake is inversely associated with systemic inflammation and the prevalence of the metabolic syndrome in middle-aged and older women.”

Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women

Mg intake ▼  Chronic Inflammation markers ▲  -CRP is a test for inflammation level.

–   According to the USDA - “Both decreased magnesium intakes and blood magnesium levels have been associated with an increased marker of chronic inflammation in people of all ages.Numerous studies have shown that a low magnesium status occurs often in people with diseases that have a chronic inflammation component, includingheart disease, diabetes, high blood pressure, and osteoporosis.”


–   “Most Americans consume magnesium at levels below the RDA. Individuals with intakes below the RDA are more likely to have elevated CRP, which may contribute to cardiovascular disease risk.”

Dietary magnesium and C-reactive protein levels.

–   "Conclusion: The results of this study show that low serum magnesium levels are independently related to elevated CRP concentration, in non-diabetic, non-hypertensive obese subjects."

Relationship between serum magnesium levels and C-reactive protein concentration, in non-diabetic, non-hypertensive obese subjects

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