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Over 300 Enzymes Need Magnesium to Function
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Mg2+-dependent
enzymes appear in virtually every metabolic pathway
Helps maintain normal muscle and nerve
function (works together
with calcium) –
Mg affects cell mechanisms controlling
muscle and nerve cell activity.
–
Mg orchestrates the electric current that
sparks through the body's miles of nerves
–
Mg serves as “gatekeeper”to stop calcium
entering into and activating a nerve - with Mg
deficiency, the nerve can become over-activated, which can cause muscle
tension, soreness, spasms, cramps and fatigue, migraine, and spastic
lower esophageal and pyloric
sphincter function leading to GERD;
–
Mg promotes normal bowel function
– Keeps heart rhythm
steady
(the heart is a muscle) - Research suggests that cardiac muscle (the
heart) is more sensitive to magnesium intake than skeletal muscle.
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Supports a healthy immune system -
fighting infection
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Promotes proper/strong formation of bones
and teeth
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Helps regulate blood sugar levels -intracellular enzyme tyrosine kinase
needs Mg to allow insulin to lower
blood sugar
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Promotes normal blood pressure – Mg stimulates production of prostacyclins and
nitric oxide (NO) –both potent artery-relaxing agents.
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Key involvement in cellular ATP energy
production
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Involved in metabolism of protein,
carbohydrates and fats - Mg
is
required for the binding of thiamine (vitamin B1) to thiamine-using
enzymes within the cell.
Thiamine pyrophosphate (TPP) is a coenzyme in the catabolism (breakdown)
of sugars and amino acids;
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Converts
Vitamin D to CALCITRIOL (its active form) –crucial
in many health functions
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Involved in protein synthesis
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Other enzymes that rely on
Mg
-
creatine-kinase activation,
adenylate-cyclase, and sodium-potassium-ATPase
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Mg
helps transport other minerals across cell membranes
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