Heal Yourself At Home
Magnesium Menubar
Magnesium (Mg) Calms Nerves

Mg Calms Nerves

- Magnesium has a calming effect on the nervous system

The neurological effects of Mg:

–    Mg++ (at high extracellular concentration) reduces electrical excitation by diminishing synaptic transmission - achieved via blocking release of acetylcholine into the synaptic gap between neurons.


–    Mg++ reduces neuronal excitability in its role as a natural “Calcium Channel Blocker” -   Mg++ions(and other ++ cations at mM concentrations) decrease the activation of certain membrane-bound, voltage-gated calcium channels, and in limiting the influx of extracellular calcium++ into the neuronal cytosol, thereby reduce neuronal excitability.(via surface charge


–    Mg++ reduces pain - by blocking N-methyl-D-aspartate (NMDA) glutamate receptors, an excitatory neurotransmitter of the central nervous system; prevents ion-flow at typical neuronal resting potentials.

Mayer ML, Westbrook GL. Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. J Physiol 1987; 394: 501–527.PubMedChemPort

Mg is a “calcium channel blocker”in neurons

Mg++ at high extracellular concentrations blocks Ca++influx and diminishes synaptic transmission

Dodge Jr FA, Rahamimoff R. Co-operative action a calcium ions in transmitter release at the neuromuscular junction. J Physiol 1967; 193: 419–432.

–    If Mg levels are low, nerves lose control over muscle activity, respiration and mental processes - nerve cells (neurons) need sufficient magnesium to give or receive messages, without which they become excitable and highly reactive. This causes the person to become highly sensitive and highly nervous, possibly resulting in:

Nervous fatigue

Tics and twitches




Muscle spasms





Irregular heartbeat

# E.g. sharp muscle reaction to an unexpected loud noise.

–    These effects manifest themselves in several well-known neurological /neuromuscular conditions - including sleep disorders, the “shakes”in alcoholics, Parkinson's disease, migraines, pre-eclampsia, suicidal tendencies, epileptic seizures, pain, SIDS, CFS and psychiatric disorders:

Magnesium for Neurological/ Neuromuscular conditions


Mg is cofactor for ATPase pumps / ATP production

ATP-producing mitochondria are highly concentrated in cells of the brain and central nervous system – since neurotransmission has an avid need for ATP energy

Mg for Cell "Battery"/ATP Production


side bar
DISCLAIMER: The content on this website is intended for informational, and educational purposes only and not as a substitute for the medical advice, treatment or diagnosis of a licensed health professional. The author of this website is a researcher, not a health professional, and shall in no event be held liable to any party for any direct, indirect, special, incidental, punitive or other damages arising from any use of the content of this website. Any references to health benefits of specifically named products on this site are this website author's sole opinion and are not approved or supported by their manufacturers or distributors. COPYRIGHT 2009-2018