Magnesium is anti-inflammatory

Magnesium needed for inflammation-controlling localized "hormones"

Magnesium (also vitamin B6 and zinc) are required for the Δ6D enzyme.   This enzyme converts essential fatty acids in foods into needed active forms, and which eventually convert to inflammation- controlling prostaglandins and leukotrienes (localized "Hormones", called eicosonoids)

Local Hormones

Magnesium intake / deficiency affects inflammatory marker CHP

Magnesium intake ↓  Chronic Inflammation marker CRP ↑ 

According to the USDA both decreased magnesium intakes and blood magnesium levels have been associated with an increased CRP in people of all ages.   Numerous studies have shown that a low magnesium status occurs often in people with diseases that have a chronic inflammation component, including heart disease, diabetes, high blood pressure, and osteoporosis.”

According to publication by King et al, "Dietary magnesium and C- reactive protein levels":

"Most Americans consume magnesium at levels below the RDA. Individuals with intakes below the RDA are more likely to have elevated CRP, which may contribute to cardiovascular disease risk."   King et al, 2005

Another study examined the association between serum magnesium levels and C- reactive protein (CRP) in non- diabetic, non- hypertensive obese subjects. Concluding:

"The results of this study show that low serum magnesium levels are independently related to elevated CRP concentration, in non- diabetic, non- hypertensive obese subjects." Relationship study

Magnesium intake ↑  Inflammation ↓ 

Dietary magnesium connected to lowered diabetes risk.   A study by Dr. Ka He of the University of North Carolina at Chapel Hill and colleagues found a connection between dietary magnesium and a lowered risk of diabetes/decreasing INSULIN resistance - also revealed that as magnesium intake increased, inflammation levels decreased.   Dae Jung Kim, 2011

Conclusion of another study with older, middle- aged American women:

 "Our results suggest that magnesium intake is inversely associated with systemic inflammation and the prevalence of the metabolic syndrome in middle- aged and older women." Magnesium intake

References

Dae Jung Kim et al (publ. online Aug 31, 2011 ) Magnesium Intake in Relation to Systemic Inflammation, Insulin Resistance, and the Incidence of Diabetes. Diabetes Care, PubMed

King DE, Mainous AG 3rd, Geesey ME, Woolson RF (2005 Jun) Dietary magnesium and C- reactive protein levels. J Am Coll Nutr. 24(3):166- 71. Pubmed

Magnesium intake, C- reactive protein, and the prevalence of metabolic syndrome in middle- aged and older U.S. women

Relationship between serum magnesium levels and C- reactive protein concentration, in non- diabetic, non- hypertensive obese subjects