Magnesium is a Muscle Relaxant
Magnesium is a muscle relaxant in skeletal muscle contractions
Do move a muscle"101
The neuromuscular system is the combination of the nervous system and
muscles, working together to permit movement. The brain controls the movements
of skeletal (voluntary) muscles via specialized nerve cells (neurons).
move a body part. A message (an action potential) is sent to upper motor neurons, which have long tails (axons) that go into and
through the brain, and into
the spinal cord, where they connect
with lower motor neurons. At the
spinal cord, ~50-200 lower motor neurons in the spinal cord send their axons via
nerves in the arms and legs directly to the muscle they control.
Each lower motor neuron is subdivided into many tiny branches. The tip of each
branch is called a presynaptic terminal.
The connection between the tip of the nerve and the muscle is called the
The neurotransmitter ACETYLCHOLINE
triggers skeletal muscle contraction. The
electrical signal from the brain (action potential) travels down the nerves (neurons) and prompts the release of
from the presynaptic terminals. This chemical is
picked up by special sensors (receptors) in the muscle tissue. If enough
receptors are stimulated by ACETYLCHOLINE
your muscles will contract. ACETYLCHOLINE
F or skeletal muscles, the force exerted by the
muscle is controlled by varying the frequency at which action potentials are
sent to muscle fibers.
Magnesium role in muscle tension and spasms
depletion leads to increased neuronal excitability and enhanced neuromuscular
opposite effect occurs with
excess. An example of acute CNS
found in cattle with "grass staggers"(tetany), leading to severe muscle seizure
and even death. magnesium In humans, a chronic
deficit is implicated in neurological and neuromuscular conditions,
such as migraine, CFS, and many other sleep and psychiatric disorders magnesium
decrease in neuronal magnesium
concentration is postulated to increase calcium binding to prejunctional
vesicles. Increasing release of ACETYLCHOLINE into
the neuromuscular cleft and so increasing muscle contractions.
With a relative deficiency of
magnesium to calcium, calcium
remains trapped in the muscle cells. Over
time, if the relative deficiency continues (as often occurs in aging), the
muscles become more or less permanently contracted, leading to increasing muscle
tension and spasms.
Magnesium prevents soft tissue calcification