Cancer patients have notably low levels of magnesium in their bodies
(1) Cancer Treatment Core - "Cancer NOT Allowed!"
With cancer - restoring your body's magnesium
levels is a "NO BRAINER!"
Cancer patients have notably low levels of magnesium in their bodies
Studies suggest that cancer may not be able to exist in a body saturated with
magnesium ;
Radiation and chemotherapy
both deplete the body's magnesium levels
Magnesium
is a team player. You will also need to ensure that the other
nutrients on
magnesium 's "team" are not only present, but also in balanced proportion,
since they all work together. The other main team members are
Calcium , Phosphorus, Vitamins
A , D and
K . The "team" also includes
manganese , zinc
and copper.
Research suggests
that almost anyone with cancer should begin a
Calcium : Magnesium
intake ratio of 1:1 - High calcium
levels are commonly attributed to either mainstream cancer treatments or the cancer
itself, but the underlying issue is most likely magnesium
deficiency. Severe hypercalcemia can be avoided if
magnesium levels are brought up to normal.
Transdermal
Magnesium Chloride
is the first and most important item in any cancer treatment strategy.
It takes 3-4 months of transdermal
magnesium therapy
to restore cellular
magnesium levels where they need
to be, but the benefits will be experienced throughout the body's systems within
only a few days - much like quenching your thirst after being dehydrated.
Transdermal
Magnesium Chloride
Research showing general correlations between magnesium and
cancer
High magnesium
levels associated with 50% decrease in cancer mortility.
Found researchers at the Lille Pasteur Institute in a study
of > 4,000 men over an 18-year follow up period. (Also a 40% decrease in cardiovascular
and all-cause mortality). (Epidemiology
2006 )
In solid tumors a high level of supplemented
magnesium inhibits carcinogenesis
(Durlach 1986 )
Researchers found that 46% of the patients admitted to the
ICU of a cancer center presented with Mg deficiency
(Deheinzelin 2000 )
Magnesium seems to
be protective against cancer - both cancer cells and
magnesium deficiency show a dramatically impaired
ionic flux between the outer and inner cell membranes i.e. higher
Ca and Na; lower
magnesium and K
levels. Lead (Pb) salts caused more leukemia cells when given to
magnesium deficient rats,
than when they are given to
magnesium -adequate rats,
suggesting that
magnesium protects against cancer;
researchers concluded that inadequacy of
magnesium
and antioxidants are important risk factors
in predisposing to leukemias. (Aleksandrowicz,
1970 )
Much less magnesium
binding to cancer cells than normal cells. Using cells from induced
cancers, researchers found that there is much less magnesium (Mg++) binding to membrane
phospholipids of cancer cells, than to normal cell membranes. Mg-deficient cell
membranes have a smoother surface than normal. They also have decreased membrane
viscosity, similar to changes in human leukemia cells.
(Anghileri 1979 )
Several studies have shown an increased cancer
rate in regions with low magnesium levels
in soil and drinking water (also with low selenium
levels). E.g. in N and S of France and Italy cancer rates correlate with magnesium
deficiency in soil
Areas with a high average
magnesium intake have significantly less cancer.
In Egypt,
the cancer rate was only about 10% of that in Europe and America (and practically
non-existent in rural peasants). Average
magnesium
intake of the Egyptian cancer-free populations is 2.5-3g, > 10 x most western
countries. (Egypt 1931 )
Specific cancers correlated with magnesium deficiency
Periosteal cancer
Restoring magnesium levels caused
periosteal (fibrous connective tissue wrapped around bone)
tumors to rapidly disappear "
Hunt 1972
Colon cancer
Magnesium -rich
diets reduced the occurrence of colon cancer - conclude School
of Public Health researchers at the University of Minnesota; A study from Sweden
reported that women with the highest magnesium
intake had a 40% lower risk of developing colon cancer than those with the lowest
Mg intake. Reference?
A Vanderbuilt university study found that
low ratios of magnesium
and calcium are associated
with reduced risk of colorectal cancer. "The risk of colorectal cancer adenoma
recurrence was reduced by 32 per cent among those with baseline calcium to magnesium
ratio below the median in comparison to no reduction for those above the median,"said
Qi Dai, MD, PhD, a member of the research team.
Calcium supplementation only reduced the risk of cancer recurrence if the
ratio of calcium to magnesium was low, and
remained low during the intervention period. Both high Mg and calcium levels have
been linked to reduced risks of colon cancer, but high
calcium levels inhibit the absorption of
magnesium .
AACR ,
Nutraingredients
Leukemia
Pre-treatment hypomagnesemia has been reported
in young leukemic children. 78% of whom have histories of anorexia,
and have excessive gut and urinary losses of Mg.
Paunier,
1965
Gastric cancer
Magnesium provides
protective effect against gastric cancer - the School of Public Health
at the Kaohsiung Medical College in Taiwan found that
Mg exerts a protective effect against gastric
cancer, but only for the group with the highest levels.
Yang 1998
Prostate Cancer
Magnesium
protects against high calcium intake linked to higher risk of prostate cance.
A 1998 Harvard School of Public Health study of 47,781 men found those consuming
1,500 - 2000 mg of calcium per day had about double the risk of being diagnosed
with metastatic prostate cancer as those
getting 500 mg per day or less.Those consuming > 2,000 mg had over four times
the risk of developing metastatic prostate cancer as those taking in less than 500
mg.
Breast cancer
Magnesium
deficiency - The missing link between alcohol consumption and increased risk of
breast cancer? Magnesium -deficiency is a
known consequence of alcohol consumption. Wine, beer and liquor add equally to the
risk of women developing breast cancer. Women who had one or two drinks a day increased
their risk of developing breast cancer by 10%. More than three drinks a day raised
their risk by 30 percent. Klatsky 2007
According to data published in the British Journal of Cancer in 2002, 4% of all
breast cancers (~4,000 cases a year) in the U.K. are due to alcohol consumption.
Maybe it is not the alcohol itself causing these cancers, but rather
the effects of magnesium depletion caused by
the alcohol? Yes, we know that a drink or two protects against heart attacks, but
it seems that magnesium supplementation may
be necessary to avoid an increased cancer risk.
Magnesium has multiple anti-cancer roles
Magnesium has multiple essential roles, which need to be "played"
to avoid setting the stage for the creation, growth and metastasis of cancer cells:
Magnesium Function
Cancer Relevance
> 300 Enzymes Need
Magnesium to Function These enzymes are needed for all the following cancer-related functions
and many of the body's other life-sustaining chemical interconversions.
Maintains mitochondrial
ATP production and Cell membrane "Battery"
Most of the enzymes involved in mitochondrial
ATP energy production require magnesium .
ATP provides the power to actively transport
ions across the plasma membrane, necessary to remove waste/heavy metals
from the cell and to maintain the cell "battery"level (by
transporting Na+ and K+ ions against their concentration gradient).
Low ATP production is a hallmark of cancer.
Needed for fatty
acid and phospholipid metabolism To maintain cell membrane integrity and prevent cell infection (evidence
is mounting that microbial infection of cells is involved in cancer);
it is thought that Mg deficiency increases plasma membrane (cell membrane
interfacing with extracellular fluid) permeability and fluidity affecting
ion transport across cell membrane.
Needed for production
of glutathione (body's primary antioxidant and detoxifier of cell
cytoplasm) Glutathione detoxifies toxins, including heavy metals, which increase
oxidant damage to cells, recognized
as a factor in cancer. Glutathione is a powerful antioxidant, helps
red blood cells carry oxygen and is needed for the creation and maintenance
of T-cell lymphocytes -the immune system's frontline defense against
infection.
Counteracts calcification
of cell membranes Up to 30% of cellular energy production is used to pump calcium
out of the cells. A healthy cell has high Mg/ Low calcium levels, but
a lower ATP energy output means less
calcium is pumped out of cell. Calcium accumulation on the inner cell
membrane (called calcification) of various tissue cells manifests in
many of the health problems seen today, including cancer. Calcification
of the membrane interferes with ion transport into and out of the cell
and with waste removal from the cell.
Facilitates hormone
uptake and release Hormonal imbalance is a recognized factor in cancer;
Alkalizing agent
Cancer cells can not survive in an alkaline environment
Heavy metal detoxification
Heavy metal presence increases oxidant damage in body. Damage to
cell membranes and genetic components are involved in cancer.
Needed to convert vitamin
D to its active form Many studies now confirm the ability of vitamin D to significantly
protect against cancer
References
Aleksandrowicz, J., Blicharski, J., Dzigowska,
A., Lisiewicz, J. Leuko- and oncogenesis in the light of studies on metabolism of
magnesium and its turnover in biocenosis. Acta Med. Pol. 1970; 11:289-302. (abstr:
Blood 1971; 37:245)
Anghileri, L.J. Magnesium concentration variations during carcinogenesis. Magnesium
Bull. 1979; 1:46-48.
Article
http://www.mgwater.com/rod02.shtml
Hunt, B.J., Belanger, L.F. Localized, multiform, sub-periosteal hyperplasia and
generalized osteomyelosclerosis in magnesium-deficient rats. Calcif. Tiss. Res.
1972; 9:17-27.
www.nutraingredients.com/Research/Magnesium-may-be-key-to-calcium-s-cancer-benefits-study
Yang CY et al. Jpn J Cancer Res.1998
Feb;89 (2):124-30. Calcium, magnesium, and nitrate in drinking water and gastric
cancer mortality.
